The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia (Q24810655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16396835%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia (English)

1 reference

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15 January 2020

0 references

4

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15 January 2020

author name string

Bert Schepens

1

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15 January 2020

Sandrine A Tinton

2

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15 January 2020

Yanik Bruynooghe

3

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15 January 2020

Sigrid Cornelis

5

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15 January 2020

language of work or name

English

0 references

publication date

7 December 2005

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15 January 2020

published in

Nucleic Acids Research

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15 January 2020

volume

33

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15 January 2020

issue

21

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15 January 2020

page(s)

6884-6894

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UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein

15 January 2020

cites work

1 reference

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Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

7 April 2017

1 reference

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Polypyrimidine tract binding protein and poly r(C) binding protein 1 interact with the BAG-1 IRES and stimulate its activity in vitro and in vivo

7 April 2017

1 reference

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Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

7 April 2017

1 reference

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Human insulin-like growth factor II leader 2 mediates internal initiation of translation

7 April 2017

1 reference

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Differentiation-induced internal translation of c-sis mRNA: analysis of the cis elements and their differentiation-linked binding to the hnRNP C protein

7 April 2017

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Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA

7 April 2017

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 April 2017

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Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes

7 April 2017

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A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

7 April 2017

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

7 April 2017

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Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures

7 April 2017

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Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

7 April 2017

1 reference

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The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr

7 April 2017

1 reference

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Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function

7 April 2017

1 reference

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

7 April 2017

1 reference

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

7 April 2017

1 reference

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

7 April 2017

1 reference

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

7 April 2017

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

7 April 2017

1 reference

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Purification and characterization of hypoxia-inducible factor 1

7 April 2017

1 reference

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Molecular mechanisms of translation initiation in eukaryotes

7 April 2017

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

7 April 2017

1 reference

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

7 April 2017

1 reference

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Polypyrimidine tract-binding protein enhances the internal ribosomal entry site-dependent translation of p27Kip1 mRNA and modulates transition from G1 to S phase

7 April 2017

1 reference

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Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: roles of Unr (upstream of N-ras) protein and phosphorylated translation initiation factor eIF-2alpha

28 September 2017

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ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

28 September 2017

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The 5' untranslated region of protein kinase Cdelta directs translation by an internal ribosome entry segment that is most active in densely growing cells and during apoptosis

28 September 2017

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Translation of polioviral mRNA is inhibited by cleavage of polypyrimidine tract-binding proteins executed by polioviral 3C(pro)

28 September 2017

1 reference

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A 5' Leader of Rbm3, a Cold Stress-induced mRNA, Mediates Internal Initiation of Translation with Increased Efficiency under Conditions of Mild Hypothermia

28 September 2017

1 reference

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Protein factor requirements of the Apaf-1 internal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras

28 September 2017

1 reference

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A cell cycle-dependent protein serves as a template-specific translation initiation factor

28 September 2017

1 reference

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A cell cycle-dependent internal ribosome entry site

28 September 2017

1 reference

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Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites

28 September 2017

1 reference

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Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Post-transcriptional regulation: the dawn of PTB.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

PDGF2/c-sis mRNA leader contains a differentiation-linked internal ribosomal entry site (D-IRES).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Alternative Translation Initiation of the Moloney Murine Leukemia Virus mRNA Controlled by Internal Ribosome Entry Involving the p57/PTB Splicing Factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Optimization of experimental variables influencing reporter gene expression in hepatoma cells following calcium phosphate transfection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Polypyrimidine-tract binding protein (PTB) is necessary, but not sufficient, for efficient internal initiation of translation of human rhinovirus-2 RNA

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Internal initiation of translation mediated by the 5′ leader of a cellular mRNA

30 May 2018

1 reference

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Porcine polypyrimidine tract-binding protein stimulates translation initiation at the internal ribosome entry site of foot-and-mouth-disease virus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Pyrimidine tract binding protein strongly stimulates in vitro encephalomyocarditis virus RNA translation at the level of preinitiation complex formation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310900

Gel retardation and UV-crosslinking assays to detect specific RNA-protein interactions in the 5' or 3' UTRs of translationally regulated mRNAs

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16396835

12 December 2020

inferred from PubMed ID database lookup

Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16396835

12 December 2020

inferred from PubMed ID database lookup

Polypyrimidine tract-binding protein inhibits translation of bip mRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16396835

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKI1000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16396835%20AND%20SRC:MED&resulttype=core&format=json

release_tr5e7aq3dfhcbfzk43egrswxze

15 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tr5e7aq3dfhcbfzk43egrswxze

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16396835%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

16396835

1 reference