Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1 (Q24812880)

5 July 2017

Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1 (English)

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5 July 2017

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Sarah A Steer

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5 July 2017

Anna L Scarim

series ordinal

2

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5 July 2017

Kari T Chambers

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3

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5 July 2017

John A Corbett

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4

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5 July 2017

language of work or name

English

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publication date

20 December 2005

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5 July 2017

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5 July 2017

3

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5 July 2017

e17

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5 July 2017

2

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Creative Commons Attribution 4.0 International

5 July 2017

start time

20 December 2005

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

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Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

7 April 2017

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Mechanisms of caspase activation

7 April 2017

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Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

7 April 2017

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RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

7 April 2017

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The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells

7 April 2017

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Induction of a Common Pathway of Apoptosis by Staurosporine

7 April 2017

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7 April 2017

Caspases: enemies within

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

7 April 2017

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Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

7 April 2017

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HMGB1 is an endogenous immune adjuvant released by necrotic cells

7 April 2017

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

28 September 2017

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28 September 2017

Chromatin and cell death

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Reversing established sepsis with antagonists of endogenous high-mobility group box 1.

28 September 2017

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

28 September 2017

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Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Apoptotic signal transduction pathways in diabetes

28 September 2017

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

28 September 2017

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The machinery of programmed cell death.

28 September 2017

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beta-Cell death during progression to diabetes

28 September 2017

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New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal

28 September 2017

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beta-cell apoptosis: stimuli and signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Apoptotic signal transduction: emerging pathways

28 September 2017

1 reference

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IL-1 produced and released endogenously within human islets inhibits beta cell function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

The role of interleukin-1 in the pathogenesis of IDDM.

28 September 2017

1 reference

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The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

28 September 2017

1 reference

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Heat shock protein hsp70 overexpression confers resistance against nitric oxide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Cytokines and nitric oxide in islet inflammation and diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Insulin-dependent diabetes mellitus as an autoimmune disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Essential fatty acid deficiency depletes rat glomeruli of resident macrophages and inhibits angiotensin II-induced eicosanoid synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Electrophysiology of stimulus-secretion coupling in human beta-cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Essential fatty acid depletion of renal allografts and prevention of rejection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1beta.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

CD4+ and CD8+ T lymphocytes: clarification of their pathogenic roles in diabetes in the NOD mouse

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

North-American twins with IDDM. Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Toxicity determined in vitro by morphological alterations and neutral red absorption

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Activation of intraislet lymphoid cells causes destruction of islet cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

The intraislet macrophage and type I diabetes.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Strain-dependent difference in inducible nitric oxide synthesis (iNOS) expression in rat pancreatic islets correlates with interferon regulating factor 1 (IRF-1) and heat shock protein 70 (HSP70) expression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Pancreatic beta-cell damage mediated by beta-cell production of interleukin-1. A novel mechanism for virus-induced diabetes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316065

The role of cytokines as effectors of tissue destruction in autoimmunity

28 November 2018

1 reference

12 December 2020

Isolation of islets of Langerhans from rodent pancreas

1 reference

12 December 2020

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

12 December 2020

Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets

1 reference

12 December 2020

Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo

1 reference

12 December 2020

Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin Vivo

1 reference

12 December 2020

Activation of human neonatal monocyte-derived dendritic cells by lipopolysaccharide down-regulates birch allergen-induced Th2 differentiation

1 reference

12 December 2020

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

1 reference

12 December 2020

Diabetes in identical twins. A study of 200 pairs

1 reference

12 December 2020

Cytokines cause functional and structural damage to isolated islets of Langerhans

1 reference

12 December 2020

Measurement of human IL-1 by LIF induction, pancreatic islet-cell cytotoxicity, and bone resorption

1 reference

12 December 2020

Species differences in human and rat islet sensitivity to human cytokines. Monoclonal anti-interleukin-1 (IL-1) influences on direct and indirect IL-1-mediated islet effects

1 reference

12 December 2020

Strain-Dependent Differences in Sensitivity of Rat -Cells to Interleukin 1 In Vitro and In Vivo

1 reference

12 December 2020

Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis

1 reference

12 December 2020

Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes

1 reference

12 December 2020

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

1 reference

12 December 2020

10.1371/JOURNAL.PMED.0030017

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DOI

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5 July 2017

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5 July 2017

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