Molecular mechanisms of hepatitis C virus-induced hepatocellular carcinoma (Q26740423)

Europe PubMed Central

title

Molecular mechanisms of hepatitis C virus-induced hepatocellular carcinoma (English)

0 references

0 references

1 reference

hepatocellular carcinoma

1 reference

1 reference

5

0 references

Gian Maria Fimia

4

0 references

Giulia Refolo

object named as

Giulia Refolo

2

0 references

Tiziana Vescovo

1

object named as

Tiziana Vescovo

0 references

author name string

Grazia Vitagliano

Clinical Microbiology and Infection

3

0 references

publication date

28 July 2016

0 references

published in

0 references

cites work

Plasma transforming growth factor-beta 1 in patients with hepatocellular carcinoma. Comparison with chronic liver diseases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The angiogenic makeup of human hepatocellular carcinoma does not favor vascular endothelial growth factor/angiopoietin-driven sprouting neovascularization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Calpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus promotes T-helper (Th)17 responses through thymic stromal lymphopoietin production by infected hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Polymorphisms of the core, NS3, and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Human OX40 tunes the function of regulatory T cells in tumor and nontumor areas of hepatitis C virus-infected liver tissue.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Atorvastatin and fluvastatin are associated with dose-dependent reductions in cirrhosis and hepatocellular carcinoma, among patients with hepatitis C virus: Results from ERCHIVES.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Chronic viral hepatitis induced by hepatitis C but not hepatitis B virus infection correlates with increased liver angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Host genetic variants influencing the clinical course of hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

TNF-α and IL-10 polymorphisms increase the risk to hepatocellular carcinoma in HCV infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Serum concentrations of sIL-2R, IL-6, TGF-beta1, neopterin, and zinc in chronic hepatitis C patients treated with interferon-alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV infection induces mitochondrial bioenergetic unbalance: causes and effects

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

A lymphotoxin-driven pathway to hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Immunity, Inflammation, and Cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Genetic polymorphism of IL-23R influences susceptibility to HCV-related hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

A polymorphism in interferon L3 is an independent risk factor for development of hepatocellular carcinoma after treatment of hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Human viral oncogenesis: a cancer hallmarks analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

How do persistent infections with hepatitis C virus cause liver cancer?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

High tumor necrosis factor-α/interleukin-10 ratio is associated with hepatocellular carcinoma in patients with chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Early changes in dynamic biomarkers of liver fibrosis in hepatitis C virus-infected patients treated with sofosbuvir

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

MicroRNAs: Role in Hepatitis C Virus pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Studies on the role of NS3 and NS5A non-structural genes of hepatitis C virus genotype 3a local isolates in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

TERT promoter mutation in resectable hepatocellular carcinomas: a strong association with hepatitis C infection and absence of hepatitis B infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Immune responses to HCV and other hepatitis viruses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus-induced hepatocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Risk of HCC: genetic heterogeneity and complex genetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Innate and adaptive immune responses in HCV infections

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Natural history of hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus hijacks host lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Impaired autophagy response in human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

1 reference

7 January 2021

Hepatitis C virus NS5A protein protects against TNF-alpha mediated apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Angiopoietin and Tie signaling pathways in vascular development

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Unravelling mechanisms of p53-mediated tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatocellular carcinoma: A global view.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Exploration of liver cancer genomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Ambra1 at the crossroad between autophagy and cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Epigenetic changes in virus-associated human cancers.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core variants isolated from liver tumor but not from adjacent non-tumor tissue interact with Smad3 and inhibit the TGF-beta pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Polymorphisms near the IFNL3 Gene Associated with HCV RNA Spontaneous Clearance and Hepatocellular Carcinoma Risk

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Parallel expression profiling of hepatic and serum microRNA-122 associated with clinical features and treatment responses in chronic hepatitis C patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Transforming growth factor-beta 1 in chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Steatosis in chronic hepatitis C: Association with increased messenger RNA expression of collagen I, tumor necrosis factor-alpha and cytochrome P450 2E1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Autophagy protects cells from HCV-induced defects in lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Epidemiology of viral hepatitis and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Curing chronic hepatitis C--the arc of a medical triumph

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The autophagy machinery is required to initiate hepatitis C virus replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Diminished viral replication and compartmentalization of hepatitis C virus in hepatocellular carcinoma tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Abnormal structure and expression of p53 gene in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The impact of the revolution in hepatitis C treatment on hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Role of transforming growth factor-beta signaling in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus Genotype 1a core gene nucleotide patterns associated with hepatocellular carcinoma risk.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS5A protein interacts with beta-catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Autophagy-deficient mice develop multiple liver tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Expression of Beclin-1, an autophagy-related marker, in chronic hepatitis and hepatocellular carcinoma and its relation with apoptotic markers

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Improvement of liver function parameters in advanced HCV-associated liver cirrhosis by IFN-free antiviral therapies

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Mitochondrial reactive oxygen species as a mystery voice in hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Impact of PNPLA3 polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatic steatosis and hepatitis C: Still unhappy bedfellows?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor-κB/hypoxia-inducible factor-1α axis under hypoxic conditions

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Liver-infiltrating CD8(+) lymphocytes as prognostic factor for tumour recurrence in hepatitis C virus-related hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Should surveillance for liver cancer be modified in hepatitis C patients after treatment-related cirrhosis regression?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Impaired Replication of Hepatitis C Virus Containing Mutations in a Conserved NS5B Retinoblastoma Protein-Binding Motif

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

New Mechanism of Hepatic Fibrogenesis: Hepatitis C Virus Infection Induces Transforming Growth Factor β1 Production through Glucose-Regulated Protein 94.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Apoptosis: a mechanism of acute and chronic liver injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Microvessel density and clinicopathological characteristics in hepatitis C virus and hepatitis B virus related hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Autophagy in HCV infection: keeping fat and inflammation at bay

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatocellular carcinoma from an immunologic perspective

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Characterization of chronic HCV infection-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Enhancement of canonical Wnt/β-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus NS2 protein inhibits DNA damage pathway by sequestering p53 to the cytoplasm.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Autophagy in malignant transformation and cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Induction of autophagy promotes the growth of early preneoplastic rat liver nodules

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Epigenetic instability and chromosomal instability in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Role of oxidative stress in hepatocarcinogenesis induced by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV and oxidative stress in the liver.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

HCV core protein uses multiple mechanisms to induce oxidative stress in human hepatoma Huh7 cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Effect of hepatitis C virus nonstructural protein NS3 on proliferation and MAPK phosphorylation of normal hepatocyte line

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Epigenetics in hepatocellular carcinoma: an update and future therapy perspectives

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Angiogenic activity of hepatitis B and C viruses.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Hepatitis C virus core protein induces hypoxia-inducible factor 1α-mediated vascular endothelial growth factor expression in Huh7.5.1 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Influence of vascular endothelial growth factor and alpha-fetoprotein on hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Chronic HCV infection and inflammation: Clinical impact on hepatic and extra-hepatic manifestations

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Oxidative stress modulation in hepatitis C virus infected cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021

Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMI.2016.07.019

7 January 2021