Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin (Q26770578)

http://europepmc.org/abstract/PMC/6514469

30 June 2019

title

Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin (English)

1 reference

http://europepmc.org/abstract/PMC/6514469

30 June 2019

main subject

dilated cardiomyopathy

1 reference

11

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11 June 2020

Tural Aksel

2

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11 June 2020

Jongmin Sung

8

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11 June 2020

Rebecca E Taylor

13

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11 June 2020

author name string

James A Spudich

1

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11 June 2020

Sadie R Bartholomew

3

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11 June 2020

Suman Nag

4

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11 June 2020

Masataka Kawana

5

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11 June 2020

Elizabeth Choe Yu

6

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11 June 2020

Saswata S Sarkar

7

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11 June 2020

Ruth F Sommese

9

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11 June 2020

Shirley Sutton

10

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11 June 2020

Arjun S Adhikari

12

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11 June 2020

Chao Liu

14

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11 June 2020

Darshan Trivedi

15

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11 June 2020

Kathleen M Ruppel

16

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11 June 2020

language of work or name

English

0 references

publication date

1 January 2016

1 reference

http://europepmc.org/abstract/PMC/6514469

30 June 2019

number of pages

7

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The Journal of Experimental Biology

inferred from page(s)

published in

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11 June 2020

volume

219

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11 June 2020

issue

Pt 2

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11 June 2020

page(s)

161-167

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Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy

11 June 2020

cites work

1 reference

12 December 2020

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy

1 reference

12 December 2020

Protein domain interfaces: characterization and comparison with oligomeric protein interfaces

1 reference

12 December 2020

A simple method for measuring the relative force exerted by myosin on actin filaments in the in vitro motility assay: evidence that tropomyosin and troponin increase force in single thin filaments

1 reference

12 December 2020

A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin

1 reference

12 December 2020

Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation

1 reference

12 December 2020

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

1 reference

12 December 2020

Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy

1 reference

12 December 2020

Structural and functional studies of titin’s fn3 modules reveal conserved surface patterns and binding to myosin S1 - a possible role in the frank-starling mechanism of the heart

1 reference

12 December 2020

Different functional properties of troponin T mutants that cause dilated cardiomyopathy

1 reference

12 December 2020

Actin-binding proteins regulate the work performed by myosin II motors on single actin filaments

1 reference

12 December 2020

Myosin crossbridge activation of cardiac thin filaments: implications for myocardial function in health and disease

1 reference

12 December 2020

Binding of myosin binding protein-C to myosin subfragment S2 affects contractility independent of a tether mechanism

1 reference

12 December 2020

Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties

1 reference

12 December 2020

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

1 reference

12 December 2020

Calcium, thin filaments, and the integrative biology of cardiac contractility

1 reference

12 December 2020

Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype

1 reference

12 December 2020

Regulation of muscle contraction by tropomyosin and troponin: how structure illuminates function

1 reference

12 December 2020

Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay

1 reference

12 December 2020

Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations

1 reference

12 December 2020

Tropomyosin: function follows structure

1 reference

12 December 2020

A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation

1 reference

12 December 2020

Cardiomyopathy: a systematic review of disease-causing mutations in myosin heavy chain 7 and their phenotypic manifestations

1 reference

12 December 2020

Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?

1 reference

12 December 2020

The molecular basis of frictional loads in the in vitro motility assay with applications to the study of the loaded mechanochemistry of molecular motors

1 reference

12 December 2020

Insights into human beta-cardiac myosin function from single molecule and single cell studies

1 reference

12 December 2020

Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry

1 reference

12 December 2020

Binding of the N-terminal fragment C0-C2 of cardiac MyBP-C to cardiac F-actin

1 reference

12 December 2020

Structure and interactions of myosin-binding protein C domain C0: cardiac-specific regulation of myosin at its neck?

1 reference

12 December 2020

Cardiac myosin activation: a potential therapeutic approach for systolic heart failure

1 reference

12 December 2020

Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history

1 reference

12 December 2020

Thin filament mutations: developing an integrative approach to a complex disorder

1 reference

12 December 2020

Smooth muscle myosin cross-bridge interactions modulate actin filament sliding velocity in vitro

1 reference

12 December 2020

The cell biology of disease: cellular mechanisms of cardiomyopathy.

1 reference

12 December 2020

Molecular motors: forty years of interdisciplinary research

1 reference

12 December 2020

Truncations of titin causing dilated cardiomyopathy.

1 reference

12 December 2020

Identification of functional differences between recombinant human α and β cardiac myosin motors

1 reference

12 December 2020

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

1 reference

12 December 2020

Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor

1 reference

12 December 2020

One path to understanding energy transduction in biological systems

1 reference

12 December 2020

Titin is a major human disease gene

1 reference

12 December 2020

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function

1 reference

12 December 2020

Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T

1 reference

12 December 2020

Dilated cardiomyopathy: the complexity of a diverse genetic architecture.

1 reference

12 December 2020

Cardiac titin and heart disease

1 reference

12 December 2020

Lysine and arginine content of proteins: computational analysis suggests a new tool for solubility design.

1 reference

12 December 2020

The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin

1 reference

12 December 2020

Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin

1 reference

12 December 2020

Earning stripes: myosin binding protein-C interactions with actin

1 reference

12 December 2020

Altered interactions between cardiac myosin binding protein-C and α-cardiac actin variants associated with cardiomyopathies

1 reference

12 December 2020

Structural implications of β-cardiac myosin heavy chain mutations in human disease

1 reference

12 December 2020

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells

1 reference

12 December 2020

Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies.

1 reference

12 December 2020

Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium

1 reference

12 December 2020

Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.

1 reference

12 December 2020

The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy

1 reference

12 December 2020

New perspectives on the prevalence of hypertrophic cardiomyopathy

1 reference

12 December 2020

Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector

1 reference

12 December 2020

Myosin subfragment-1 is sufficient to move actin filaments in vitro

1 reference

12 December 2020

Fluorescent actin filaments move on myosin fixed to a glass surface

1 reference

12 December 2020

Movement of myosin-coated beads on oriented filaments reconstituted from purified actin

1 reference

12 December 2020

Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults

1 reference

12 December 2020

Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments

1 reference

12 December 2020

Are actin filaments moving under unloaded conditions in the in vitro motility assay?

1 reference

12 December 2020

Single myosin molecule mechanics: piconewton forces and nanometre steps

1 reference

12 December 2020

Calponin decreases the rate of cross-bridge cycling and increases maximum force production by smooth muscle myosin in an in vitro motility assay

1 reference

12 December 2020

The neck region of the myosin motor domain acts as a lever arm to generate movement

1 reference

12 December 2020

Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy

1 reference

12 December 2020

The Genetic Basis for Cardiomyopathy

1 reference

12 December 2020

Mechanism of Muscular Contraction

1 reference

Crossref

https://api.crossref.org/works/10.1242%2FJEB.125930

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1242/JEB.125930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792326%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792326%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

26792326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792326%20AND%20SRC:MED&resulttype=core&format=json