Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? (Q28264798)

Europe PubMed Central

title

Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? (English)

0 references

author

Michelle S Parvatiyar

4

object named as

Michelle S Parvatiyar

0 references

author name string

Ruth H Willott

1

0 references

Aldrin V Gomes

2

0 references

Audrey N Chang

3

0 references

Jose Renato Pinto

5

0 references

James D Potter

Journal of Molecular and Cellular Cardiology

6

0 references

language of work or name

English

0 references

publication date

May 2010

0 references

published in

0 references

volume

48

0 references

issue

5

0 references

page(s)

882-92

0 references

cites work

Muscle proteins--their actions and interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mechanism of adenosine triphosphate hydrolysis by actomyosin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Troponin and tropomyosin: proteins that switch on and tune in the activity of cardiac myofilaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The troponin complex and regulation of muscle contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Troponin, tropomyosin, and actin interactions in the Ca2+ regulation of muscle contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca2+ and activation mechanisms in skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca(2+)-regulated structural changes in troponin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Crossbridge and tropomyosin positions observed in native, interacting thick and thin filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered interactions among thin filament proteins modulate cardiac function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A new look at thin filament regulation in vertebrate skeletal muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction11Edited by W. Baumeister

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca(2+)-induced switching of troponin and tropomyosin on actin filaments as revealed by electron cryo-microscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

An atomic model of the thin filament in the relaxed and Ca2+-activated states.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Calcium-dependent changes in the flexibility of the regulatory domain of troponin C in the troponin complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Structural changes in troponin in response to Ca2+ and myosin binding to thin filaments during activation of skeletal muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The muscle thin filament as a classical cooperative/allosteric regulatory system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cooperativity and switching within the three-state model of muscle regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial hypertrophic cardiomyopathy: from mutations to functional defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Sudden death in young athletes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Asymmetrical hypertrophy of the heart in young adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cardiomyopathies: from genetics to the prospect of treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Sudden death in hypertrophic cardiomyopathy. Assessment of patients at high risk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Aetiology, diagnosis, investigation, and management of the cardiomyopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Contractile protein mutations and heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Sudden death due to troponin T mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Novel missense mutation in cardiac troponin T gene found in Japanese patient with hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Many roads lead to a broken heart: the genetics of dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The Genetic Basis for Cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The Frequency of Familial Dilated Cardiomyopathy in a Series of Patients with Idiopathic Dilated Cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Frequency and phenotypes of familial dilated cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial dilated cardiomyopathy in the United Kingdom

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Gene mutations in adult Japanese patients with dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Clinical profile and outcome of idiopathic restrictive cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Morphologic spectrum of primary restrictive cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

New insights into the pathology of inherited cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Restrictive Cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial restrictive cardiomyopathy with skeletal abnormalities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Converging pathways and principles in heart development and disease: CV@CSH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Clinical and molecular studies of a large family with desmin-associated restrictive cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Idiopathic restrictive cardiomyopathy in children is caused by mutations in cardiac sarcomere protein genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

First mutation in cardiac troponin C, L29Q, in a patient with hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Designing calcium-sensitizing mutations in the regulatory domain of cardiac troponin C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Spectroscopic analysis of a methionine-48 to tyrosine mutant of chicken troponin C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Troponin-C mutants with increased calcium affinity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in the N- and D-helices of the N-domain of troponin C affect the C-domain and regulatory function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca2+, Mg2+, and troponin I inhibitory peptide binding to a Phe-154 to Trp mutant of chicken skeletal muscle troponin C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Different functional properties of troponin T mutants that cause dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional analysis of a troponin I (R145G) mutation associated with familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Troponin I: inhibitor or facilitator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional analyses of troponin T mutations that cause hypertrophic cardiomyopathy: insights into disease pathogenesis and troponin function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Effects of missense mutations Phe110Ile and Glu244Asp in human cardiac troponin T on force generation in skinned cardiac muscle fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Regulation of contraction in striated muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Reciprocal coupling between troponin C and myosin crossbridge attachment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Modulation of troponin C affinity for the thin filament by different cross-bridge states in skinned skeletal muscle fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Structural coupling of troponin C and actomyosin in muscle fibers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

R-92L and R-92W mutations in cardiac troponin T lead to distinct energetic phenotypes in intact mouse hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Regulation of cardiac hypertrophy by intracellular signalling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Functional effects of a restrictive-cardiomyopathy-linked cardiac troponin I mutation (R145W) in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Altered contractile function in heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Diastolic Dysfunction in Congestive Heart Failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Myofibrillar adenosine triphosphatase activity in congestive heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Origin of contractile dysfunction in heart failure: calcium cycling versus myofilaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Molecular mechanisms of inherited cardiomyopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Comparison of fluorescent SSCP and denaturing HPLC analysis with direct sequencing for mutation screening in hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Phenotypic differences between electrocardiographic and echocardiographic determination of hypertrophic cardiomyopathy in genetically affected subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Clinical manifestations of hypertrophic cardiomyopathy with mutations in the cardiac beta-myosin heavy chain gene or cardiac troponin T gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Codon 102 of the cardiac troponin T gene is a putative hot spot for mutations in familial hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Frequency of cardiac troponin I mutations in families with hypertrophic cardiomyopathy in China

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cardiac troponin I mutations in Australian families with hypertrophic cardiomyopathy: clinical, genetic and functional consequences.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cytosine methylation confers instability on the cardiac troponin T gene in hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Myosin binding protein C mutations and compound heterozygosity in hypertrophic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Patients with familial hypertrophic cardiomyopathy caused by a Phe110Ile missense mutation in the cardiac troponin T gene have variable cardiac morphologies and a favorable prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Prevalence and clinical profile of troponin T mutations among patients with hypertrophic cardiomyopathy in tuscany

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Hypertrophic cardiomyopathy: low frequency of mutations in the beta-myosin heavy chain (MYH7) and cardiac troponin T (TNNT2) genes among Spanish patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Identification of the genotypes causing hypertrophic cardiomyopathy in northern Sweden

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

A novel mutation Lys273Glu in the cardiac troponin T gene shows high degree of penetrance and transition from hypertrophic to dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Late-onset hypertrophic cardiomyopathy caused by a mutation in the cardiac troponin T gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Low prevalence of cardiac troponin T mutations in a Greek hypertrophic cardiomyopathy cohort

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Coding sequence mutations identified in MYH7, TNNT2, SCN5A, CSRP3, LBD3, and TCAP from 313 patients with familial or idiopathic dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Deletion in TNNI3 gene is associated with restrictive cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Cardiac troponin T lysine 210 deletion in a family with dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

Infantile restrictive cardiomyopathy resulting from a mutation in the cardiac troponin T gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

inferred from DOI database lookup

7 January 2021

based on heuristic

Ca2+-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.10.031

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YJMCC.2009.10.031

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

19914256

1 reference

Consolidated OpenCitations Corpus – April 2017