RND-type drug eﬄux pumps from Gram-negative bacteria: molecular mechanism and inhibition (Q26827930)

main subject

Gram-negative bacteria

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1

Henrietta Venter

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Rumana Mowla

2

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Thelma Ohene-Agyei

series ordinal

3

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Shutao Ma

series ordinal

4

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language of work or name

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2015

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Frontiers in Microbiology

published in

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volume

6

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page(s)

377

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Structure of the AcrAB–TolC multidrug efflux pump

cites work

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Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

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Tackling antibiotic resistance

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Mechanism and Function of the Outer Membrane Channel TolC in Multidrug Resistance and Physiology of Enterobacteria

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Artesunate enhances the antibacterial effect of {beta}-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC.

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Geraniol restores antibiotic activities against multidrug-resistant isolates from gram-negative species.

28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

An ABC transporter with a secondary-active multidrug translocator domain

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

High-level triclosan resistance in Pseudomonas aeruginosa is solely a result of efflux

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4412071

An alkylaminoquinazoline restores antibiotic activity in Gram-negative resistant isolates

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25972857

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Acceleration of emergence of bacterial antibiotic resistance in connected microenvironments

1 reference

https://pubmed.ncbi.nlm.nih.gov/25972857

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FMICB.2015.00377

1 reference

1 reference

1 reference

PubMed publication ID

25972857

1 reference