BH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions (Q26828031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22230093%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

BH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22230093%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

1 reference

Victoria Del Gaizo Moore

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22230093%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Anthony Letai

series ordinal

2

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22230093%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

1 reference

8 January 2012

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20 January 2020

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20 January 2020

volume

332

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20 January 2020

issue

2

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20 January 2020

page(s)

202-205

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BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

20 January 2020

cites work

1 reference

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

7 April 2017

1 reference

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

7 April 2017

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

7 April 2017

1 reference

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BAX activation is initiated at a novel interaction site

7 April 2017

1 reference

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

7 April 2017

1 reference

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

7 April 2017

1 reference

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

7 April 2017

1 reference

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770266

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

7 April 2017

1 reference

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

7 April 2017

1 reference

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The Bcl2 family: regulators of the cellular life-or-death switch

7 April 2017

1 reference

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Induction of apoptosis in fibroblasts by c-myc protein

7 April 2017

1 reference

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Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes.

7 April 2017

1 reference

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MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts

28 September 2017

1 reference

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Control of mitochondrial apoptosis by the Bcl-2 family

28 September 2017

1 reference

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Rational design of therapeutics targeting the BCL-2 family: are some cancer cells primed for death but waiting for a final push?

28 September 2017

1 reference

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Quantitative analysis of pathways controlling extrinsic apoptosis in single cells

28 September 2017

1 reference

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Diagnosing and exploiting cancer's addiction to blocks in apoptosis

28 September 2017

1 reference

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BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.

28 September 2017

1 reference

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Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

28 September 2017

1 reference

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The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.

28 September 2017

1 reference

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Structural biology of the Bcl-2 family of proteins

28 September 2017

1 reference

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A view to a kill: ligands for Bcl-2 family proteins

28 September 2017

1 reference

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

28 September 2017

1 reference

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Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

28 September 2017

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Three-dimensional structures of proteins involved in programmed cell death

28 September 2017

1 reference

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The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

31 May 2018

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Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

31 May 2018

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Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

31 May 2018

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A matter of life and death

28 November 2018

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12 December 2020

Antiapoptotic BCL-2 is required for maintenance of a model leukemia

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12 December 2020

Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity

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12 December 2020

The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2

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12 December 2020

10.1016/J.CANLET.2011.12.021

Identifiers

DOI

1 reference

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20 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22230093%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

2 references