A metabolic perspective of Peto's paradox and cancer (Q26828989)

modelling biological systems

main subject

1 reference

19 September 2019

1 reference

8 February 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Chi V. Dang

series ordinal

1

1 reference

Philosophical Transactions of the Royal Society B

language of work or name

1 reference

19 July 2015

4 references

3 April 2019

19 September 2019

8 February 2021

5 references

3 April 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

8 February 2021

370

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

1673

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

page(s)

20140223

0 references

copyright license

3 references

3 April 2019

19 September 2019

on focus list of Wikimedia project

8 February 2021

copyright status

copyrighted

0 references

ScienceSource

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cites work

pH sensing and regulation in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Neutralizing tumor-promoting chronic inflammation: a magic bullet?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Links between metabolism and cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

mTOR signaling in growth control and disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Hallmarks of Cancer: The Next Generation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Understanding the Warburg effect: the metabolic requirements of cell proliferation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Scaling of number, size, and metabolic rate of cells with body size in mammals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Glutamine and cancer: cell biology, physiology, and clinical opportunities

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

A role for mitochondrial enzymes in inherited neoplasia and beyond

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

A general model for ontogenetic growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

A general model for the origin of allometric scaling laws in biology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Peto's Paradox: evolution's prescription for cancer prevention

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Sleep drives metabolite clearance from the adult brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

MYC on the path to cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

The energetics of genome complexity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

The gut microbiota, bacterial metabolites and colorectal cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Role of the Keap1-Nrf2 pathway in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Caloric restriction and cancer: molecular mechanisms and clinical implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Bioenergetic constraints on the evolution of complex life

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Oxford and the Savannah: can the hippo provide an explanation for Peto's paradox?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

TET enzymes, TDG and the dynamics of DNA demethylation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Potential applications for biguanides in oncology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Disrupting proton dynamics and energy metabolism for cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Use of somatic mutations to quantify random contributions to mouse development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Cancer cell metabolism: one hallmark, many faces.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

The role of mutations in epigenetic regulators in myeloid malignancies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Decoding cell lineage from acquired mutations using arbitrary deep sequencing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

A quantitative theory of solid tumor growth, metabolic rate and vascularization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Glutamine: pleiotropic roles in tumor growth and stress resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Histone methyl transferases and demethylases; can they link metabolism and transcription?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Body size and metabolic rate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Quantum metabolism explains the allometric scaling of metabolic rates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

From empirical patterns to theory: a formal metabolic theory of life.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Hypoxia in cancer cell metabolism and pH regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Marine mammal neoplasia: a review.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Clues to the functions of mammalian sleep

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

The fourth dimension of life: fractal geometry and allometric scaling of organisms.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Energy metabolism, body size, and problems of scaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Reconciling theories for metabolic scaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Absence of metabolic rate allometry in an ex vivo model of mammalian skeletal muscle

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Metabolic rate does not scale with body mass in cultured mammalian cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

A hierarchy of ATP-consuming processes in mammalian cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Genome sequencing of normal cells reveals developmental lineages and mutational processes

31 May 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Why don't all whales have cancer? A novel hypothesis resolving Peto's paradox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Physiology: Why does metabolic rate scale with body size?

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Curvature in metabolic scaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Testing metabolic theories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Thermodynamics of organisms in the context of dynamic energy budget theory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

The origin of allometric scaling laws in biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Scaling of oxidative and glycolytic enzymes in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Increases in amino-cupric-silver staining of the supraoptic nucleus after sleep deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Antioxidant defense responses to sleep loss and sleep recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2014.0223

Capillary density in mammals in relation to body size and oxygen consumption

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Capillary blood transit time in muscles in relation to body size and aerobic capacity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581028

Causes of differences in respiration rate of hepatocytes from mammals of different body mass

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26056367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Age distribution of cancer in mice: the incidence turnover at old age

1 reference

https://pubmed.ncbi.nlm.nih.gov/26056367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1098/RSTB.2014.0223

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

26056367

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056367%20AND%20SRC:MED&resulttype=core&format=json