Curcuminoids and resveratrol as anti-Alzheimer agents (Q26829183)

1

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Ying-Ju Chen

2

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Chih-Ping Chen

3

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Jui-Ming Yeh

4

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Tzong-Yuan Wu

5

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language of work or name

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December 2012

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Taiwanese Journal of Obstetrics & Gynecology

published in

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volume

51

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issue

4

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page(s)

515-25

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Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

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Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

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Anti-thrombotic effect of curcumin

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2.

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Identification and regulation of the high affinity binding site of the Alzheimer's disease amyloid protein precursor (APP) to glycosaminoglycans

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

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7 January 2021

The redox chemistry of the Alzheimer's disease amyloid beta peptide.

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Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

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Solid-state NMR analysis of interaction sites of curcumin and 42-residue amyloid β-protein fibrils

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Potential therapeutic effects of curcumin: relationship to microtubule-associated proteins 2 in Aβ1-42 insult

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Are mitochondria critical in the pathogenesis of Alzheimer's disease?

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7 January 2021

Resveratrol--a boon for treating Alzheimer's disease?

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7 January 2021

The effects of curcumin on depressive-like behaviors in mice

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7 January 2021

Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain

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7 January 2021

Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT).

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7 January 2021

Dual effects of curcumin on neuronal oxidative stress in the presence of Cu(II).

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7 January 2021

Review on plants with CNS-effects used in traditional South African medicine against mental diseases

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7 January 2021

Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by manganese complexes of curcumin and diacetylcurcumin.

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7 January 2021

A possible link between astrocyte activation and tau nitration in Alzheimer's disease.

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7 January 2021

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

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7 January 2021

Post-translational modifications of tau protein: implications for Alzheimer's disease.

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7 January 2021

The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells

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7 January 2021

Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain

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7 January 2021

Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

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7 January 2021

Protein quality control in Alzheimer's disease by the ubiquitin proteasome system.

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7 January 2021

Microtubule-associated protein tau in development, degeneration and protection of neurons

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Nitration of tau protein is linked to neurodegeneration in tauopathies

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7 January 2021

Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.

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7 January 2021

Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function

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7 January 2021

Global prevalence of dementia: a Delphi consensus study

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7 January 2021

Factors influencing the processing and function of the amyloid beta precursor protein--a potential therapeutic target in Alzheimer's disease?

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7 January 2021

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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7 January 2021

Plants and human health in the twenty-first century.

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7 January 2021

Enhanced BK-induced calcium responsiveness in PC12 cells expressing the C100 fragment of the amyloid precursor protein.

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7 January 2021

Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult

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7 January 2021

Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death

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7 January 2021

Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain

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7 January 2021

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

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7 January 2021

Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats

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7 January 2021

Site-specific nitration differentially influences tau assembly in vitro

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7 January 2021

Direct HPLC Analysis of cis- and trans-Resveratrol and Piceid Isomers in Spanish Red Vitis vinifera Wines

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7 January 2021

Chemical studies on antioxidant mechanism of curcuminoid: analysis of radical reaction products from curcumin

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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7 January 2021

Therapeutic potential of resveratrol: the in vivo evidence

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7 January 2021

Neurotoxicity of a carboxyl-terminal fragment of the Alzheimer's amyloid precursor protein.

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7 January 2021

Molecular evolution of tau protein: implications for Alzheimer's disease.

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7 January 2021

Cross-linking sites of the human tau protein, probed by reactions with human transglutaminase

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7 January 2021

Alzheimer's disease: the pharmacological pathway

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7 January 2021

Enhancement of wound healing by curcumin in animals

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7 January 2021

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

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7 January 2021

Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain

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7 January 2021

beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin

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7 January 2021

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

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7 January 2021

Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes

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7 January 2021

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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7 January 2021

A role for the beta-amyloid precursor protein in memory?

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7 January 2021

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

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7 January 2021

Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro

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7 January 2021

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

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7 January 2021

Effect of Pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant Tau

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7 January 2021

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

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7 January 2021

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

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7 January 2021

Cysteine oxidation of tau and microtubule-associated protein-2 by peroxynitrite: modulation of microtubule assembly kinetics by the thioredoxin reductase system

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7 January 2021

Mechanisms of soluble beta-amyloid impairment of endothelial function

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7 January 2021

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

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7 January 2021

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

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7 January 2021

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease

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7 January 2021

The distribution of tau in the mammalian central nervous system

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7 January 2021

Untangling the tau gene association with neurodegenerative disorders.

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7 January 2021

Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons

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7 January 2021

Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.

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7 January 2021

C-terminal fragment of amyloid precursor protein inhibits calcium uptake into rat brain microsomes by Mg2+-Ca2+ ATPase.

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7 January 2021

C-terminal fragment of Alzheimer's amyloid precursor protein inhibits sodium/calcium exchanger activity in SK-N-SH cell

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7 January 2021

Microtubule assembly in vitro. Purification of assembly-promoting factors.

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7 January 2021

Brain levels of microtubule-associated protein tau are elevated in Alzheimer's disease: a radioimmuno-slot-blot assay for nanograms of the protein.

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7 January 2021

Fetal-type phosphorylation of the tau in paired helical filaments

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7 January 2021

Neuronal protection by sirtuins in Alzheimer's disease

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7 January 2021

Alois Alzheimer and Alzheimer's disease: a centennial perspective.

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7 January 2021

Curcumin binds to the alpha-helical intermediate and to the amyloid form of prion protein - a new mechanism for the inhibition of PrP(Sc) accumulation

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7 January 2021

Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade

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7 January 2021

Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: influence of linker length and flexibility.

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7 January 2021

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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7 January 2021

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

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7 January 2021

Impaired spatial learning after saturation of long-term potentiation.

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7 January 2021

The primary structure and heterogeneity of tau protein from mouse brain.

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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7 January 2021

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

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7 January 2021

The Phenolic Substances of White Hellebore (Veratrum Grandiflorum Hoes. Fil.) I

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7 January 2021

Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aβ and Aβ-metal complexes toxicity

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7 January 2021

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

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7 January 2021

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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7 January 2021

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

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7 January 2021

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

1 reference

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7 January 2021