The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis (Q26852413)

S. J. Lolait

series ordinal

2

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L. E. Harris

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3

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G. R. Pope

series ordinal

4

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language of work or name

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October 2013

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published in

Journal of Endocrinology

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volume

219

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issue

1

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page(s)

R13-35

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Discovery of a competitive apelin receptor (APJ) antagonist.

cites work

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https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Design strategies for bivalent ligands targeting GPCRs

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https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The hepatic apelin system: a new therapeutic target for liver disease

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin (65-77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Expression and coreceptor function of APJ for primate immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Increased apelin serum levels and expression in human chondrocytes in osteoarthritic patients

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Interpreting cDNA sequences: some insights from studies on translation

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Regulation of reactive oxygen species generation in cell signaling

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin suppresses apoptosis of human osteoblasts

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Temporal changes in myocardial salvage kinases during reperfusion following ischemia: studies involving the cardioprotective adipocytokine apelin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is required for non-neovascular remodeling in the retina.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is a novel angiogenic factor in retinal endothelial cells

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Direct effects of apelin on cardiomyocyte contractility and electrophysiology

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Free radicals and antioxidants in normal physiological functions and human disease

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Centrally administered apelin-13 induces depression-like behavior in mice.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The 212A variant of the APJ receptor gene for the endogenous inotrope apelin is associated with slower heart failure progression in idiopathic dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Anatomical profiling of G protein-coupled receptor expression

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Heterodimerization of human apelin and kappa opioid receptors: roles in signal transduction

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is involved in postprandial responses and stimulates secretion of arginine-vasopressin, adrenocorticotropic hormone, and growth hormone in the ruminant

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Therapeutic potential of interfering with apelin signalling.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Lower serum apelin levels in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Vascular effects of apelin in vivo in man.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The endogenous, immunologically active peptide apelin inhibits lymphocytic cholinergic activity during immunological responses

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Role of helix 8 in G protein-coupled receptors based on structure-function studies on the type 1 angiotensin receptor

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

EGF receptor activation by GPCRs: an universal pathway reveals different versions

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Behavioral, neuroendocrine and thermoregulatory actions of apelin-13

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin protects heart against ischemia/reperfusion injury in rat.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The apelinergic system in the developing lung: Expression and signaling

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Central and peripheral apelin receptor distribution in the mouse: species differences with rat

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Supraspinal antinociceptive effect of apelin-13 in a mouse visceral pain model.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Neuroprotection of apelin and its signaling pathway

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Involvement of neurotransmitters in the action of apelin-13 on passive avoidance learning in mice.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Post-infarct treatment with [Pyr1]-apelin-13 reduces myocardial damage through reduction of oxidative injury and nitric oxide enhancement in the rat model of myocardial infarction.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The role of the brain renin-angiotensin system in hypertension: implications for new treatment.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Central and peripheral cardiovascular actions of apelin in conscious rats

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin cells in the rat stomach

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Regulation of apelin mRNA expression by insulin and glucocorticoids in mouse 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin and its receptor are expressed in human osteoblasts

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Utility of plasma apelin and other indices of cardiac dysfunction in the clinical assessment of patients with dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Increased colonic apelin production in rodents with experimental colitis and in humans with IBD

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin effects in human splanchnic arteries. Role of nitric oxide and prostanoids

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Ontogeny of apelin and its receptor in the rodent gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin peptides block the entry of human immunodeficiency virus (HIV).

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Molecular properties of apelin: tissue distribution and receptor binding

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-immunoreactivity in the rat hypothalamus and pituitary.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Low stringency hybridization study of the dopamine D4 receptor revealed D4-like mRNA distribution of the orphan seven-transmembrane receptor, APJ, in human brain.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Distribution of apelin-synthesizing neurons in the adult rat brain.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Differential neuronal activation in the hypothalamic paraventricular nucleus and autonomic/neuroendocrine responses to I.C.V. endotoxin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Site-specific effects of apelin-13 in the rat medulla oblongata on arterial pressure and respiration

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Structural and functional study of the apelin-13 peptide, an endogenous ligand of the HIV-1 coreceptor, APJ.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Effect of apelin on glomerular hemodynamic function in the rat kidney

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

APJ acts as a dual receptor in cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Sensitive and specific method for detecting G protein-coupled receptor mRNAs.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is a potent activator of tumour neoangiogenesis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

APJ Receptor mRNA Expression in the Rat Hypothalamic Paraventricular Nucleus: Regulation By Stress and Glucocorticoids

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Characterization of apelin, the ligand for the APJ receptor

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Changes and relations of circulating visfatin, apelin, and resistin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Low plasma apelin levels in newly diagnosed type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Akt regulates cell survival and apoptosis at a postmitochondrial level

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Identification and comparison of eleven rhesus macaque chemokine receptors

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

PI3K/Akt signaling transduction pathway is involved in rat vascular smooth muscle cell proliferation induced by apelin-13.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Glycosylation of G-protein-coupled receptors for hormones central to normal reproductive functioning: its occurrence and role.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Biology of the apelin-APJ axis in vascular formation

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

TNFalpha up-regulates apelin expression in human and mouse adipose tissue.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Characterization of the 5'-regulatory regions of the rat and human apelin genes and regulation of breast apelin by USF.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Hypoxia inducible factor regulates the cardiac expression and secretion of apelin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Genetic variants in the apelin system and blood pressure responses to dietary sodium interventions: a family-based association study

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Diminished metabolic responses to centrally-administered apelin-13 in diet-induced obese rats fed a high-fat diet

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Stimulus-specific neuroendocrine responses to osmotic challenges in apelin receptor knockout mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Modulation of the apelin/APJ system in heart failure and atherosclerosis in man

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin acts in the subfornical organ to influence neuronal excitability and cardiovascular function

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxide

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is necessary for the maintenance of insulin sensitivity

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Cellular localization of apelin and its receptor in the anterior pituitary: evidence for a direct stimulatory action of apelin on ACTH release

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Endogenous regulation of cardiovascular function by apelin-APJ.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

A possible role for hypoxia-induced apelin expression in enteric cell proliferation

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Gene regulation in the magnocellular hypothalamo-neurohypophysial system

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Cloning, pharmacological characterization and brain distribution of the rat apelin receptor

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Retardation of retinal vascular development in apelin-deficient mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin is a crucial factor for hypoxia-induced retinal angiogenesis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

[Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: vasoactive mechanisms and inotropic action in disease.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, a new enteric peptide: localization in the gastrointestinal tract, ontogeny, and stimulation of gastric cell proliferation and of cholecystokinin secretion

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Modification of the terminal residue of apelin-13 antagonizes its hypotensive action

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Dehydration-induced cross-regulation of apelin and vasopressin immunoreactivity levels in magnocellular hypothalamic neurons

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, a newly identified adipokine up-regulated by insulin and obesity

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The effects of apelin on the electrical activity of hypothalamic magnocellular vasopressin and oxytocin neurons and somatodendritic Peptide release

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Increased bone mass in mice lacking the adipokine apelin

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Altered glucose homeostasis is associated with increased serum apelin levels in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin ameliorates TNF-α-induced reduction of glycogen synthesis in the hepatocytes through G protein-coupled receptor APJ.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Aldosterone directly affects apelin expression and secretion in adipocytes

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Transcriptional regulation of the rat apelin receptor gene: promoter cloning and identification of an Sp1 site necessary for promoter activity

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

The effects of apelin on hypothalamic-pituitary-adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Abnormal fluid homeostasis in apelin receptor knockout mice

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin-13 induces a biphasic haemodynamic response and hormonal activation in normal conscious sheep

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression.

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021

Plasma apelin and ADMA Levels in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1530%2FJOE-13-0227

7 January 2021