Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism (Q26852624)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

0 references

1

1 reference

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20 January 2020

author name string

L. Darryl Quarles

series ordinal

1

1 reference

language of work or name

1 reference

17 January 2012

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Endocrinology

20 January 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

8

2 references

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20 January 2020

issue

5

2 references

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20 January 2020

page(s)

276-286

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

20 January 2020

cites work

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FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate

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Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis

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Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice

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PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop

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7 April 2017

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Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo

7 April 2017

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Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

7 April 2017

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FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

7 April 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Role of fibroblast growth factor 23 in phosphate homeostasis and pathogenesis of disordered mineral metabolism in chronic kidney disease.

28 September 2017

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28 September 2017

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Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals

28 September 2017

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28 September 2017

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Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23

28 September 2017

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1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport

28 September 2017

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28 September 2017

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Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease

28 September 2017

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Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP)

28 September 2017

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Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation

28 September 2017

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An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia.

28 September 2017

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28 September 2017

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Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders

28 September 2017

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FGF23 is processed by proprotein convertases but not by PHEX.

28 September 2017

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Regulation of gene expression by dietary Ca2+ in kidneys of 25-hydroxyvitamin D3-1 alpha-hydroxylase knockout mice

28 September 2017

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Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers

28 September 2017

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Integrative nuclear FGFR1 signaling (INFS) as a part of a universal “feed‐forward‐and‐gate” signaling module that controls cell growth and differentiation

28 September 2017

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FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting

28 September 2017

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Evidence for a bone-kidney axis regulating phosphate homeostasis

28 September 2017

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Fibroblast growth factor-23 is the phosphaturic factor in tumor-induced osteomalacia and may be phosphatonin

28 September 2017

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Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.

28 September 2017

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Analysis of recombinant Phex: an endopeptidase in search of a substrate

28 September 2017

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Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme

28 September 2017

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Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D.

31 May 2018

1 reference

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Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4489419

Thyroid hormone activates fibroblast growth factor receptor-1 in bone

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4489419

Expression of FGF23 is correlated with serum phosphate level in isolated fibrous dysplasia.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4489419

Pathogenic role of Fgf23 in Hyp mice.

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

The genomic response of the mouse kidney to low-phosphate diet is altered in X-linked hypophosphatemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Peripheral vascular calcification in long-haemodialysis patients: associated factors and survival consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

bFGF Administration Lowers the Phosphate Threshold for Mineralization in Bone Marrow Stromal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Bone anabolic effects of basic fibroblast growth factor in ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Effects of vitamin D replacement therapy on serum FGF23 concentrations in vitamin D-deficient women in short term.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Fibroblast growth factor 23 production in bone is directly regulated by 1{alpha},25-dihydroxyvitamin D, but not PTH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Regulation of fibroblast growth factor 23 production in bone in uremic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Dysregulation of renal vitamin D metabolism in the uremic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

The osteoblast: an insulin target cell controlling glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Serum FGF23 levels in normal and disordered phosphorus homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Effect of manipulating serum phosphorus with phosphate binder on circulating PTH and FGF23 in renal failure rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Inhibition of MEPE cleavage by Phex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Mineral metabolism, mortality, and morbidity in maintenance hemodialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

FGF-23 in patients with end-stage renal disease on hemodialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Circulating Fibroblast Growth Factor-23 Is Associated With Fat Mass and Dyslipidemia in Two Independent Cohorts of Elderly Individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4489419

Hypophosphatemic rickets in opsismodysplasia

28 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Pathophysiology of X-linked hypophosphatemia, tumor-induced osteomalacia, and autosomal dominant hypophosphatemia: a perPHEXing problem

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Regulation of C-terminal and intact FGF-23 by dietary phosphate in men and women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Mortality risk among hemodialysis patients receiving different vitamin D analogs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

FGF-23, vitamin D and calcification: the unholy triad

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Fibroblast Growth Factor 23 (FGF23) Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease (MMKD) Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.218

Magnitude and impact of abnormal mineral metabolism in hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS)

31 March 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249518

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249518

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRENDO.2011.218

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 January 2020

1007185994

0 references

Fatcat ID

release_tbxnomvvzvaejh74psz5uxh42y

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tbxnomvvzvaejh74psz5uxh42y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249518%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2 references