The molecular rationale of Src inhibition in colorectal carcinomas (Q26853018)

author name string

Antonios N. Gargalionis

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1

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Michalis V. Karamouzis

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2

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Athanasios G. Papavassiliou

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3

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language of work or name

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1 May 2014

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International Journal of Cancer

published in

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volume

134

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issue

9

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page(s)

2019-29

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cites work

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The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src

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Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo

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Identification of Src transformation fingerprint in human colon cancer

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Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma.

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Src kinase regulation by phosphorylation and dephosphorylation

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Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi

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Substrate stiffness and the receptor-type tyrosine-protein phosphatase alpha regulate spreading of colon cancer cells through cytoskeletal contractility

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PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation

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A switch role of Src in the biphasic EGF signaling of ER-negative breast cancer cells

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Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

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A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways

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Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik.

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Src and Ras are involved in separate pathways in epithelial cell scattering

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Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly

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c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells

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Src activation regulates anoikis in human colon tumor cell lines

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The interplay between Src family kinases and receptor tyrosine kinases

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Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

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Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

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Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer

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Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters

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Valproic acid enhances bosutinib cytotoxicity in colon cancer cells

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Overexpression of the csk gene suppresses tumor metastasis in vivo

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Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation

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Lack of activating c-SRC mutations at codon 531 in rectal cancer

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No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese

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Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization

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Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases

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RACK1 inhibits colonic cell growth by regulating Src activity at cell cycle checkpoints

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Identifiers

DOI

10.1002/IJC.28299

1 reference

Consolidated OpenCitations Corpus – April 2017

4892019

4892019

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference