Neuroendocrine differentiation in prostate cancer: a mechanism of radioresistance and treatment failure (Q26859201)

Crossref

Richard Choo

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

2015

1 reference

published in

Frontiers in Oncology

1 reference

Crossref

volume

5

1 reference

page(s)

90

1 reference

The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration

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Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

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p21-Activated kinase 4 promotes prostate cancer progression through CREB

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

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HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells

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High-dose-rate brachytherapy boost for prostate cancer: rationale and technique

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A systematic review of hypofractionation for primary management of prostate cancer

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Radiotherapy-induced plasticity of prostate cancer mobilizes stem-like non-adherent, Erk signaling-dependent cells

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High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development

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Evolution of advanced technologies in prostate cancer radiotherapy

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Targeting survivin in cancer: novel drug development approaches

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Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway

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Pushing the limits of radiation therapy for prostate cancer: where do we go next?

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Comparing dosimetric, morbidity, quality of life, and cancer control outcomes after 3D conformal, intensity-modulated, and proton radiation therapy for prostate cancer

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28 September 2017

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EGF promotes neuroendocrine-like differentiation of prostate cancer cells in the presence of LY294002 through increased ErbB2 expression independent of the phosphatidylinositol 3-kinase-AKT pathway

28 September 2017

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Critical role of N-terminal end-localized nuclear export signal in regulation of activating transcription factor 2 (ATF2) subcellular localization and transcriptional activity

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Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells

28 September 2017

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Ionizing radiation induces neuroendocrine differentiation of prostate cancer cells in vitro, in vivo and in prostate cancer patients

28 September 2017

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Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival

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Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer

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Neuroendocrine differentiation in the progression of prostate cancer

28 September 2017

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Ionizing radiation induces prostate cancer neuroendocrine differentiation through interplay of CREB and ATF2: implications for disease progression

28 September 2017

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ATF2: a transcription factor that elicits oncogenic or tumor suppressor activities

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Neuroendocrine differentiation in prostate cancer: from lab to bedside

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28 September 2017

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EGF prevents the neuroendocrine differentiation of LNCaP cells induced by serum deprivation: the modulator role of PI3K/Akt

28 September 2017

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Adrenomedullin, an autocrine/paracrine factor induced by androgen withdrawal, stimulates 'neuroendocrine phenotype' in LNCaP prostate tumor cells

28 September 2017

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Molecular biology for the radiation oncologist: the 5Rs of radiobiology meet the hallmarks of cancer

28 September 2017

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Attenuation of apoptosis by chromogranin A-induced Akt and survivin pathways in prostate cancer cells

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Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells

28 September 2017

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Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression

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Clinical implications of neuroendocrine differentiation in prostate cancer

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Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway

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The neuroendocrine phenotype in prostate cancer: basic and clinical aspects

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Epidermal growth factor-induced neuroendocrine differentiation and apoptotic resistance of androgen-independent human prostate cancer cells.

28 September 2017

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Neuroendocrine cells in prostate cancer

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Neuroendocrine differentiation in prostate cancer: implications for new treatment modalities

28 September 2017

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Inhibitory effect of IL-6-induced neuroendocrine cells on prostate cancer cell proliferation

28 September 2017

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Interleukin-6 inhibits the growth of prostate cancer xenografts in mice by the process of neuroendocrine differentiation

28 September 2017

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Ca2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells

28 September 2017

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The role of androgen deprivation therapy combined with prostate brachytherapy

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Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer

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Impact of androgen deprivation therapy on survival in men treated with radiation for prostate cancer

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Neuroendocrine differentiation in human prostate cancer. Morphogenesis, proliferation and androgen receptor status

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Neuroendocrine differentiation in prostatic carcinoma: an update on recent developments

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Activated 3',5'-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell line

28 September 2017

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STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells .

28 September 2017

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Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression

28 September 2017

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Analysis of molecular mechanisms controlling neuroendocrine cell specific transcription of the chromogranin A gene

28 September 2017

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A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos

28 September 2017

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Neuroendocrine differentiation in human prostatic tumor models

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Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP

28 September 2017

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Prostate cancer in a transgenic mouse

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Targeting CREB inhibits radiation-induced neuroendocrine differentiation and increases radiation-induced cell death in prostate cancer cells.

28 September 2017

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Plasma chromogranin A: clinical implications in patients with castrate resistant prostate cancer receiving docetaxel chemotherapy

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Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells.

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Chromogranin A predicts outcome in prostate cancer patients treated with abiraterone

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Chromogranin A staining as a prognostic variable in newly diagnosed Gleason score 7-10 prostate cancer treated with definitive radiotherapy.

28 November 2018

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Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy

28 November 2018

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Chromogranin A expression in patients with hormone naïve prostate cancer predicts the development of hormone refractory disease.

28 November 2018

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Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: a randomized controlled trial.

28 November 2018

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Prognostic significance of plasma chromogranin a levels in patients with hormone-refractory prostate cancer treated in Cancer and Leukemia Group B 9480 study

28 November 2018

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Independent prognostic role of circulating chromogranin A in prostate cancer patients with hormone-refractory disease.

28 November 2018

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NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice.

28 November 2018

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Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era.

28 November 2018

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Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells

28 November 2018

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Variation in chromogranin A serum levels during intermittent versus continuous androgen deprivation therapy for prostate adenocarcinoma

28 November 2018

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Different profiles of neuroendocrine cell differentiation evolve in the PC-310 human prostate cancer model during long-term androgen deprivation

28 November 2018

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Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype

28 November 2018

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Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer.

28 November 2018

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Neuroendocrine differentiation in carcinomas of the prostate: do neuroendocrine serum markers reflect immunohistochemical findings?

28 November 2018

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Prognostic value of neuroendocrine serum markers and PSA in irradiated patients with pN0 localized prostate cancer

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12 December 2020

Lack of prostate cancer radiosensitization by androgen deprivation

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12 December 2020

BCL-2 proto-oncogene expression in prostate cancer and its relationship to the prostatic neuroendocrine cell

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Function and molecular mechanisms of neuroendocrine cells in prostate cancer

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12 December 2020

Neuroendocrine cell differentiation in the CWR22 human prostate cancer xenograft: association with tumor cell proliferation prior to recurrence

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12 December 2020

Androgen deprivation of the PC-310 [correction of prohormone convertase-310] human prostate cancer model system induces neuroendocrine differentiation

1 reference

12 December 2020

Prognostic significance of neuroendocrine expression in lymph node-positive prostate cancer

1 reference

12 December 2020

Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy

1 reference

12 December 2020

Risk-based management of prostate cancer

1 reference

12 December 2020

Chromogranin A is a potential prognostic marker in prostate cancer patients treated with enzalutamide

1 reference

12 December 2020

Prognostic significance of neuroendocrine differentiation in patients with Gleason score 8-10 prostate cancer treated with primary radiotherapy

1 reference

12 December 2020

Neuroendocrine cells in human prostate over-express the anti-apoptosis protein survivin

1 reference

12 December 2020

Circulating neuroendocrine markers in patients with prostate carcinoma

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Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer

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Changes in chromogranin a serum levels during endocrine therapy in metastatic prostate cancer patients

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Identifiers

DOI

10.3389/FONC.2015.00090

1 reference

1 reference

1 reference

PubMed publication ID

25927031

1 reference