New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases (Q26866194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

review article

1 reference

title

New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Christian Hölscher

series ordinal

1

1 reference

Crossref

language of work or name

1 reference

1 November 2014

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

Neural Regeneration Research

26 February 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

9

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

issue

21

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

1870-1873

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales

26 February 2020

cites work

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Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

21 March 2017

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Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

21 March 2017

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21 March 2017

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New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease.

28 September 2017

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Neurotrophic and neuroprotective efficacy of intranasal GDNF in a rat model of Parkinson's disease.

28 September 2017

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Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

28 September 2017

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28 September 2017

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Protective effect of leptin and ghrelin against toxicity induced by amyloid-β oligomers in a hypothalamic cell line.

28 September 2017

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28 September 2017

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Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

28 September 2017

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Exenatide and the treatment of patients with Parkinson's disease

28 September 2017

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Trophic factor gene therapy for Parkinson's disease

28 September 2017

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

28 September 2017

1 reference

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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers

28 September 2017

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Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

28 September 2017

1 reference

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Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery

28 September 2017

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Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

28 September 2017

1 reference

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Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease

28 September 2017

1 reference

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Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

28 September 2017

1 reference

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β-Amyloid impairs axonal BDNF retrograde trafficking

28 September 2017

1 reference

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Brain-derived neurotrophic factor in neurodegenerative diseases

28 September 2017

1 reference

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Incretin-based therapies for type 2 diabetes mellitus

28 September 2017

1 reference

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Development of a non invasive NGF-based therapy for Alzheimer's disease.

28 September 2017

1 reference

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Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

28 September 2017

1 reference

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Neurotrophic factors--a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases?

28 September 2017

1 reference

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Nerve growth factor, neural stem cells and Alzheimer's disease

28 September 2017

1 reference

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Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study

28 September 2017

1 reference

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The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease.

28 September 2017

1 reference

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Cellular delivery of NGF does not alter the expression of beta-amyloid immunoreactivity in young or aged nonhuman primates.

31 May 2018

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Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease.

31 May 2018

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Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson's disease

19 June 2018

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The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease.

28 November 2018

1 reference

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TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

28 November 2018

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Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice

28 November 2018

1 reference

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Alzheimer's failure raises questions about disease-modifying strategies

28 November 2018

1 reference

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Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults.

28 November 2018

1 reference

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Intranasal insulin improves cognition and modulates beta-amyloid in early AD.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281420

Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

28 November 2018

1 reference

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Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype

28 November 2018

1 reference

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Hope for AD with NGF gene-therapy trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281420

Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281420

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

28 November 2018

1 reference

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Amyloid beta oligomers induce impairment of neuronal insulin receptors

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25558231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4103/1673-5374.145342

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558231%20AND%20SRC:MED&resulttype=core&format=json