Apelin-APJ signaling: a potential therapeutic target for pulmonary arterial hypertension (Q27010531)

G protein-coupled receptor

inferred from title

pulmonary hypertension

5 references

22 March 2019

31 July 2019

20 November 2019

15 December 2019

10 September 2020

cell surface receptor

1 reference

31 July 2019

1 reference

20 November 2019

1 reference

15 December 2019

1 reference

10 September 2020

Jongmin Kim

1

1 reference

Crossref

language of work or name

1 reference

March 2014

1 reference

1 March 2014

5 references

22 March 2019

31 July 2019

20 November 2019

15 December 2019

10 September 2020

6 references

22 March 2019

31 July 2019

20 November 2019

15 December 2019

10 September 2020

37

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issue

3

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page(s)

196-201

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Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

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21 March 2017

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Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

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A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

21 March 2017

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AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension

21 March 2017

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Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility

21 March 2017

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The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

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Characterization of apelin, the ligand for the APJ receptor

21 March 2017

1 reference

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Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo

21 March 2017

1 reference

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Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin

21 March 2017

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Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release

21 March 2017

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Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats

21 March 2017

1 reference

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Molecular properties of apelin: tissue distribution and receptor binding

21 March 2017

1 reference

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Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development

21 March 2017

1 reference

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An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

28 September 2017

1 reference

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Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report

28 September 2017

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Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension

28 September 2017

1 reference

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Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

28 September 2017

1 reference

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Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension

28 September 2017

1 reference

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Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy.

28 September 2017

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Endothelin receptor antagonists for pulmonary arterial hypertension: an overview

28 September 2017

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Reversible or irreversible remodeling in pulmonary arterial hypertension

28 September 2017

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Genetics and genomics of pulmonary arterial hypertension

28 September 2017

1 reference

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Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

28 September 2017

1 reference

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Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents

28 September 2017

1 reference

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Insulin resistance in pulmonary arterial hypertension

28 September 2017

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Role of microRNAs in vascular diseases, inflammation, and angiogenesis

28 September 2017

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Pathobiology of pulmonary hypertension

28 September 2017

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In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure

28 September 2017

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Transcriptional regulation of the rat apelin receptor gene: promoter cloning and identification of an Sp1 site necessary for promoter activity

28 September 2017

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The discovery of nitric oxide and its role in vascular biology

28 September 2017

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PDGF signaling in pulmonary arterial hypertension

28 September 2017

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28 September 2017

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Endothelial dysfunction in pulmonary hypertension

28 September 2017

1 reference

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Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin

28 September 2017

1 reference

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The pathobiology of pulmonary hypertension. Endothelium

28 September 2017

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

28 September 2017

1 reference

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Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969039

Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension

28 September 2017

1 reference

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MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach

28 September 2017

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The cancer paradigm of severe pulmonary arterial hypertension

31 May 2018

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31 May 2018

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Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

31 May 2018

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Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969039

Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation.

28 November 2018

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Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells

28 November 2018

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Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction

28 November 2018

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Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension.

28 November 2018

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Identifiers

DOI

0 references

1 reference

PubMed publication ID

24608803

1 reference