The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. (Q39669238)

13 September 2017

The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. (English)

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13 September 2017

M E Behrens

1

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13 September 2017

P M Grandgenett

2

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13 September 2017

J M Bailey

3

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13 September 2017

P K Singh

4

1 reference

13 September 2017

C-H Yi

5

1 reference

13 September 2017

F Yu

6

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13 September 2017

M A Hollingsworth

7

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13 September 2017

language of work or name

English

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publication date

9 August 2010

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13 September 2017

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13 September 2017

29

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13 September 2017

42

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13 September 2017

5667-5677

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https://scigraph.springernature.com/pub.10.1038/onc.2010.327

13 September 2017

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cites work

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MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

14 September 2017

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The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

14 September 2017

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MUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathway

14 September 2017

1 reference

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MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.

14 September 2017

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Connective tissue growth factor (CTGF) and cancer progression

14 September 2017

1 reference

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The cytoplasmic tail of MUC1: a very busy place

14 September 2017

1 reference

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Loss of fibulin-2 expression is associated with breast cancer progression

14 September 2017

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Cell surface-associated mucins in signal transduction

14 September 2017

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Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

14 September 2017

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MUC1 expression in primary and metastatic pancreatic cancer cells for in vitro treatment by (213)Bi-C595 radioimmunoconjugate

14 September 2017

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Mucins in cancer: protection and control of the cell surface

14 September 2017

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The CCN family: a new stimulus package

14 September 2017

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Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays

14 September 2017

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The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

14 September 2017

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The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin

14 September 2017

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Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin

14 September 2017

1 reference

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MUC1 Knockdown With RNA Interference Inhibits Pancreatic Cancer Growth

14 September 2017

1 reference

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Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression

14 September 2017

1 reference

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Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling

14 September 2017

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Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

P53 down-regulates matrix metalloproteinase-1 by targeting the communications between AP-1 and the basal transcription complex

25 September 2017

1 reference

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Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

17 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells.

17 June 2018

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Correlation between CA19-9 production in vitro and histological grades of differentiation in vivo in clones isolated from a human pancreatic cancer cell line (SUIT-2)

17 June 2018

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Insulin-like growth factor-1 isoforms in rat hepatocytes and cholangiocytes and their involvement in protection against cholestatic injury

17 June 2018

1 reference

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Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

Connective tissue growth factor and its regulation in the peritoneal cavity of peritoneal dialysis patients

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412169

Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.

21 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Overexpression of MUC1 reconfigures the binding properties of tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.327

Sialylated MUC1 mucin expression in normal pancreas, benign pancreatic lesions, and pancreatic ductal adenocarcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20697347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20697347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.327

1 reference

release_4evuot3nandcbn55iikt7auoji

13 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4evuot3nandcbn55iikt7auoji

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

13 September 2017

1 reference