Differential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issues (Q27015135)

1

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Ana L. Cavatorta

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Marina Bugnon Valdano

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Federico Marziali

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Daniela Gardiol

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language of work or name

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October 2012

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279

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PubMed

issue

19

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PubMed

page(s)

3538-48

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Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

PubMed

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Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

21 January 2018

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Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

21 January 2018

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Polarity complex proteins

21 January 2018

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The PDZ protein discs-large (DLG): the 'Jekyll and Hyde' of the epithelial polarity proteins

21 January 2018

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The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

21 January 2018

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Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

MAGI-1: a widely expressed, alternatively spliced tight junction protein

21 January 2018

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

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Cloning and functional analysis of the promoter region of the human Disc large gene

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation

21 January 2018

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Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-beta during the process of epithelial to mesenchymal transition in rat proximal epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

TGF-{beta}-induced MiR-491-5p expression promotes Par-3 degradation in rat proximal tubular epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Identification of MAGI1 as a tumor-suppressor protein induced by cyclooxygenase-2 inhibitors in colorectal cancer cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease

21 January 2018

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miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.

21 January 2018

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Two classes of tight junctions are revealed by ZO-1 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Isoforms of the polarity protein par6 have distinct functions

21 January 2018

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Regulation of translational efficiency by different splice variants of the Disc large 1 oncosuppressor 5'-UTR.

21 January 2018

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Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis.

21 January 2018

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Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Human scribble accumulates in colorectal neoplasia in association with an altered distribution of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

hScrib, a human homolog of Drosophila neoplastic tumor suppressor, is involved in the progress of endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

An association analysis of synapse-associated protein 97 (SAP97) gene in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

DMDM: domain mapping of disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

A specificity map for the PDZ domain family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Expression of tight junction molecules in breast carcinomas analysed by array PCR and immunohistochemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Microdeletions of 3q29 confer high risk for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

3q29 microdeletion syndrome: clinical and molecular characterization of a new syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Expanding the clinical phenotype of the 3q29 microdeletion syndrome and characterization of the reciprocal microduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

1.3 Mb de novo deletion in chromosome band 3q29 associated with normal intelligence in a child.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Abnormal distribution of hDlg and PTEN in premalignant lesions and invasive cervical cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Epigenetics of acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Loss of tight junction plaque molecules in breast cancer tissues is associated with a poor prognosis in patients with breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X

Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08699.X