The PDZ protein discs-large (DLG): the 'Jekyll and Hyde' of the epithelial polarity proteins (Q38030668)

27 August 2017

title

The PDZ protein discs-large (DLG): the 'Jekyll and Hyde' of the epithelial polarity proteins (English)

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27 August 2017

Elizabeth Marsh

3

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Sally Roberts

object named as

Sally Roberts

series ordinal

1

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author name string

Craig Delury

series ordinal

2

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27 August 2017

language of work or name

English

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publication date

29 August 2012

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27 August 2017

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27 August 2017

volume

279

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27 August 2017

issue

19

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27 August 2017

page(s)

3549-3558

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Role of the MAGUK protein family in synapse formation and function.

27 August 2017

cites work

1 reference

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Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila.

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Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

21 January 2018

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

DLG-1 is a MAGUK similar to SAP97 and is required for adherens junction formation

21 January 2018

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Zonula adherens formation in Caenorhabditis elegans requires dlg-1, the homologue of the Drosophila gene discs large

21 January 2018

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Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis

21 January 2018

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Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

21 January 2018

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Apical junctional complexes and cell polarity

21 January 2018

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Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

21 January 2018

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Skin tight: cell adhesion in the epidermis of Caenorhabditis elegans

21 January 2018

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Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene

21 January 2018

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Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter

21 January 2018

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Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases

21 January 2018

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Functional expression of rat synapse-associated proteins SAP97 and SAP102 in Drosophila dlg-1 mutants: effects on tumor suppression and synaptic bouton structure.

21 January 2018

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Differential expression of human Dlg in cervical intraepithelial neoplasias

21 January 2018

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Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy

21 January 2018

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Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

21 January 2018

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Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

21 January 2018

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A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Human papillomaviruses and the specificity of PDZ domain targeting.

21 January 2018

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Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor

21 January 2018

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Differential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issues

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The distribution and function of alternatively spliced insertions in hDlg

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Changes in localization of human discs large (hDlg) during keratinocyte differentiation are [corrected] associated with expression of alternatively spliced hDlg variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

p38gamma regulates interaction of nuclear PSF and RNA with the tumour-suppressor hDlg in response to osmotic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Phosphorylation of the discs large tumour suppressor protein controls its membrane localisation and enhances its susceptibility to HPV E6-induced degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

ERK5 pathway regulates the phosphorylation of tumour suppressor hDlg during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

CDK phosphorylation of the discs large tumour suppressor controls its localisation and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The high-risk HPV E6 oncoprotein preferentially targets phosphorylated nuclear forms of hDlg

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Regulation of the DLG tumor suppressor by β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Functional involvement of human discs large tumor suppressor in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

The MEK2-binding tumor suppressor hDlg is recruited by E-cadherin to the midbody ring

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Redistribution of the discs large tumor suppressor protein during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Polarity sets the stage for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Identification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-large

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Characterization of PDZ-binding kinase, a mitotic kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Critical roles of T-LAK cell-originated protein kinase in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Cytokinesis, ploidy and aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

Large-scale characterization of HeLa cell nuclear phosphoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08729.X

10.1111/J.1742-4658.2012.08729.X

21 January 2018

Identifiers

DOI

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27 August 2017

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