Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS (Q27021649)

language of work or name

1 reference

March 2015

1 reference

British Journal of Pharmacology

published in

1 reference

volume

172

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issue

6

1 reference

page(s)

1397-414

1 reference

Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

21 March 2017

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S-nitrosylation in cardiovascular signaling

21 March 2017

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Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite

21 March 2017

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NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

21 March 2017

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The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

21 March 2017

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A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

21 March 2017

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Phosphodiesterases and cardiac cGMP: evolving roles and controversies

21 March 2017

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Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase

21 March 2017

1 reference

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Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB

21 March 2017

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NO-donating aspirin inhibits intestinal carcinogenesis in Min (APC(Min/+)) mice

21 March 2017

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Nitric oxide synthases: structure, function and inhibition

21 March 2017

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Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

21 March 2017

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Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1

21 March 2017

1 reference

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Fluorescence dequenching makes haem-free soluble guanylate cyclase detectable in living cells

21 March 2017

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Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats

21 March 2017

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Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

21 March 2017

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Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension

7 April 2017

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The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

28 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors

28 September 2017

1 reference

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The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.

28 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

28 September 2017

1 reference

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YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Riociguat: first global approval

28 September 2017

1 reference

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Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase

28 September 2017

1 reference

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Adipose tissue browning and metabolic health

28 September 2017

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Soluble guanylate cyclase stimulators in pulmonary hypertension

28 September 2017

1 reference

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The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems

28 September 2017

1 reference

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The chemistry and biology of soluble guanylate cyclase stimulators and activators

28 September 2017

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Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections

28 September 2017

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Riociguat for the treatment of pulmonary arterial hypertension

28 September 2017

1 reference

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Riociguat for the treatment of chronic thromboembolic pulmonary hypertension

28 September 2017

1 reference

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Nitrite in organ protection

28 September 2017

1 reference

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Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study.

28 September 2017

1 reference

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Protein kinase G oxidation is a major cause of injury during sepsis.

28 September 2017

1 reference

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Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

The regulation of vascular tetrahydrobiopterin bioavailability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Uncoupling of endothelial NO synthase in atherosclerosis and vascular disease

28 September 2017

1 reference

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Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Tadalafil alleviates muscle ischemia in patients with Becker muscular dystrophy.

28 September 2017

1 reference

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Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

28 September 2017

1 reference

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Riociguat for interstitial lung disease and pulmonary hypertension: a pilot trial.

28 September 2017

1 reference

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The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype

28 September 2017

1 reference

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Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme

28 September 2017

1 reference

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Soluble guanylate cyclase: a potential therapeutic target for heart failure

28 September 2017

1 reference

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Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?

28 September 2017

1 reference

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Structure and regulation of soluble guanylate cyclase

28 September 2017

1 reference

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Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease

28 September 2017

1 reference

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Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

28 September 2017

1 reference

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Arginase II inhibition prevents nitrate tolerance.

28 September 2017

1 reference

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Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases.

28 September 2017

1 reference

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Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis

28 September 2017

1 reference

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Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

28 September 2017

1 reference

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COXIBs, CINODs and H₂S-releasing NSAIDs: current perspectives in the development of safer non steroidal anti-inflammatory drugs

28 September 2017

1 reference

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Novel therapeutic targets for the treatment of heart failure.

28 September 2017

1 reference

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Mechanisms of disease: pulmonary arterial hypertension.

28 September 2017

1 reference

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Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Human neuroglobin functions as a redox-regulated nitrite reductase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

New perspectives for the treatment of pulmonary hypertension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitrite regulation of shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Inorganic nitrate and the cardiovascular system.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action

28 September 2017

1 reference

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A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Tadalafil for the treatment of pulmonary arterial hypertension.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

28 September 2017

1 reference

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Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitrate and nitrite in biology, nutrition and therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Recent advances in arginine metabolism: roles and regulation of the arginases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

sGC(alpha)1(beta)1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NO-independent, haem-dependent soluble guanylate cyclase stimulators

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Sildenafil: a review of its use in pulmonary arterial hypertension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Function and dysfunction of CNG channels: insights from channelopathies and mouse models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitric oxide and mitochondrial signaling: from physiology to pathophysiology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial.

28 September 2017

1 reference

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Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

28 September 2017

1 reference

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The nitric oxide/cGMP signaling pathway in pulmonary hypertension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Subcellular targeting and trafficking of nitric oxide synthases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Function of cGMP-dependent protein kinases as revealed by gene deletion.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

A detrimental role for nitric oxide synthase-2 in the pathology resulting from acute cerebral injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Overview of phosphodiesterase 5 inhibition in erectile dysfunction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitric oxide-releasing nonsteroidal anti-inflammatory drugs: novel gastrointestinal-sparing drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

NO-aspirins: a class of new anti-inflammatory and antithrombotic agents.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Purified soluble guanylyl cyclase expressed in a baculovirus/Sf9 system: stimulation by YC-1, nitric oxide, and carbon monoxide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Inducible nitric oxide synthase: what difference does it make?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitric oxide and arthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Enhanced anti-inflammatory potency of a nitric oxide-releasing prednisolone derivative in the rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Defective smooth muscle regulation in cGMP kinase I-deficient mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Inhaled nitric oxide in persistent pulmonary hypertension of the newborn

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin

31 May 2018

1 reference

Targeting heme-oxidized soluble guanylate cyclase in experimental heart failure

21 January 2018

1 reference

The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

21 January 2018

1 reference

Nitric oxide up-regulates the glucocorticoid receptor and blunts the inflammatory reaction in porcine endotoxin sepsis

21 January 2018

1 reference

Inhibition of TGF-beta induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase

21 January 2018

1 reference

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

21 January 2018

1 reference

Tadalafil therapy for pulmonary arterial hypertension.

21 January 2018

1 reference

PDE5 inhibition with sildenafil improves left ventricular diastolic function, cardiac geometry, and clinical status in patients with stable systolic heart failure: results of a 1-year, prospective, randomized, placebo-controlled study

21 January 2018

1 reference

Phosphodiesterase 5 inhibition with sildenafil reverses exercise oscillatory breathing in chronic heart failure: a long-term cardiopulmonary exercise testing placebo-controlled study

21 January 2018

1 reference

Nitric oxide inhalation and glucocorticoids as combined treatment in human experimental endotoxemia

21 January 2018

1 reference

Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial.

21 January 2018

1 reference

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

21 January 2018

1 reference

Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache.

21 January 2018

1 reference

Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.

21 January 2018

1 reference

Effects of dietary nitrate on blood pressure in healthy volunteers.

21 January 2018

1 reference

Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta

21 January 2018

1 reference

Clinical potential of combined organic nitrate and phosphodiesterase type 5 inhibitor in treatment-resistant hypertension

21 January 2018

1 reference

Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands

21 January 2018

1 reference

cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

21 January 2018

1 reference

Drotrecogin alfa (activated) in adults with septic shock.

21 January 2018

1 reference

Secondary growth of a cortical necrosis: effect of NOS inhibition by aminoguanidine post insult

21 January 2018

1 reference

Guanylyl cyclase activator ataciguat improves vascular function and reduces platelet activation in heart failure

21 January 2018

1 reference

Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase

21 January 2018

1 reference

Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial

21 January 2018

1 reference

The novel nitric oxide synthase inhibitor 4-amino-tetrahydro-L-biopterine prevents brain edema formation and intracranial hypertension following traumatic brain injury in mice.

21 January 2018

1 reference

Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia

21 January 2018

1 reference

The effect of peroxynitrite on the catalytic activity of soluble guanylyl cyclase

21 January 2018

1 reference

Measuring oxidative burden and predicting pharmacological response in coronary artery disease patients with a novel direct activator of haem-free/oxidised sGC

21 January 2018

1 reference

Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans

21 January 2018

1 reference

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes

21 January 2018

1 reference

Generation of Nitric Oxide by a Nitrite Reductase Activity of Xanthine Oxidase: A Potential Pathway for Nitric Oxide Formation in the Absence of Nitric Oxide Synthase Activity

21 January 2018

1 reference

Guidelines for the diagnosis and treatment of pulmonary hypertension.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4369253

Selective Inducible Nitric Oxide Synthase Inhibition Has No Effect on Allergen Challenge in Asthma

28 November 2018

1 reference

Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis

21 January 2018

1 reference

12 December 2020

Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions

1 reference

12 December 2020

Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated heart failure

1 reference

12 December 2020

Effects of naproxcinod on blood pressure in patients with osteoarthritis

1 reference

12 December 2020

Arginine deficiency accompanies persistent pulmonary hypertension of the newborn

1 reference

12 December 2020

Inhaled nitric oxide for the adult respiratory distress syndrome

1 reference

12 December 2020

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

1 reference

12 December 2020

Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites

1 reference

12 December 2020

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

1 reference

12 December 2020

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

1 reference

12 December 2020

Chronic Inhibition of cGMP Phosphodiesterase 5A Improves Diabetic Cardiomyopathy

1 reference

12 December 2020

Soluble guanylate cyclase from rat lung exists as a heterodimer

1 reference

12 December 2020

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling

1 reference

12 December 2020

Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus

1 reference

12 December 2020

NSAIDs, risks, and gastroprotective strategies: current status and future

1 reference

12 December 2020

Identifiers

0 references

1 reference

PubMed publication ID

25302549

1 reference