Modulation of the maladaptive stress response to manage diseases of protein folding (Q27313626)

1

0 references

Darren M Hutt

2

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Jiansong Tong

3

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Marion Bouchecareilh

4

0 references

Ning Wang

5

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Theo Seeley

6

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Johanna F Dekkers

7

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Jeffrey M Beekman

8

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Dan Garza

9

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Lawrence Drew

10

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Richard I Morimoto

12

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William E Balch

Creative Commons Attribution 4.0 International

13

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language of work or name

English

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publication date

November 2014

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published in

PLOS Biology

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volume

12

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issue

11

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page(s)

e1001998

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copyright license

start time

18 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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21 March 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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A chaperone trap contributes to the onset of cystic fibrosis

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

28 September 2017

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28 September 2017

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Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates

28 September 2017

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28 September 2017

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Chaperone networks: tipping the balance in protein folding diseases

28 September 2017

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28 September 2017

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Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein

28 September 2017

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Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking

28 September 2017

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28 September 2017

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28 September 2017

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A highly sensitive assay for monitoring the secretory pathway and ER stress

28 September 2017

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Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

28 September 2017

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Polyglutamine-mediated neurodegeneration: use of chaperones as prevention strategy

28 September 2017

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Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance

28 September 2017

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Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival

28 September 2017

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Heat shock factor 1 as a coordinator of stress and developmental pathways

28 September 2017

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Protein-misfolding diseases and chaperone-based therapeutic approaches

28 September 2017

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Progressive disruption of cellular protein folding in models of polyglutamine diseases.

28 September 2017

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Heat shock response modulators as therapeutic tools for diseases of protein conformation

28 September 2017

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A new pharmacology--drugging stressed folding pathways.

28 September 2017

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Genome-wide analysis of the biology of stress responses through heat shock transcription factor

28 September 2017

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The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response

28 September 2017

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Chaperones increase association of tau protein with microtubules

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Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists

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The regulatory domain of human heat shock factor 1 is sufficient to sense heat stress

28 September 2017

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Expression of heat shock proteins in Alzheimer's disease

28 September 2017

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Heat shock: the role of transient inducible responses in cell damage, transformation, and differentiation

28 September 2017

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Principles of cotranslational ubiquitination and quality control at the ribosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Fixing cystic fibrosis by correcting CFTR domain assembly

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

An atypical unfolded protein response in heat shocked cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Q-bodies monitor the quinary state of the protein fold

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Systemic stress signalling: understanding the cell non-autonomous control of proteostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Firefly luciferase mutants as sensors of proteome stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Trigger factor lacking the PPIase domain can enhance the folding of eukaryotic multi-domain proteins in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Function of trigger factor and DnaK in multidomain protein folding: increase in yield at the expense of folding speed

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Temporal requirements of heat shock factor-1 for longevity assurance

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

An Adaptable Standard for Protein Export from the Endoplasmic Reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001998

Well-differentiated human airway epithelial cell cultures.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Stress-induced inhibition of protein synthesis initiation: modulation of initiation factor 2 and guanine nucleotide exchange factor activities following transient cerebral ischemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236052

Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model

28 November 2018

1 reference

12 December 2020

Inhibiting the transcription factor HSF1 as an anticancer strategy

1 reference

12 December 2020

Interaction of the Hsp110 molecular chaperones from S. cerevisiae with substrate protein

1 reference

12 December 2020

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

1 reference

12 December 2020

Increased expression of heat-shock protein 27 kDa in Alzheimer disease: a preliminary study

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.1001998

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

25406061

1 reference