Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice (Q27318356)

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English	Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice	scientific article

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Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice (English)

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Anthony Dorling

object named as

Anthony Dorling

6

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author name string

Fang Xiao

1

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Liang Ma

2

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Min Zhao

3

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Guocai Huang

4

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Vincenzo Mirenda

5

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Robert Lechler

7

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Giovanna Lombardi

8

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publication date

2014

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9

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3

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e90387

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copyright license

Creative Commons Attribution 4.0 International

3 March 2014

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April 2022 Public Data File from Crossref

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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

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CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

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T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

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Humanized NOD/SCID/IL2Rgamma(null) mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesis

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Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model

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Regulatory T cells and immune tolerance in the intestine

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The role of complement in CD4⁺ T cell homeostasis and effector functions

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Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection

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Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations

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T regulatory cell separation for clinical application.

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Regulatory immune cells in transplantation

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Molecular mechanisms of treg-mediated T cell suppression

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Humanized mice: current states and perspectives

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Adoptive transfer with in vitro expanded human regulatory T cells protects against porcine islet xenograft rejection via interleukin-10 in humanized mice

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Human lymphohematopoietic reconstitution and immune function in immunodeficient mice receiving cotransplantation of human thymic tissue and CD34(+) cells

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Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF.

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Immunological applications of stem cells in type 1 diabetes

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Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells

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Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

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Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

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Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.

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Long-Term Renal Allograft Survival in the United States: A Critical Reappraisal

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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

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In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells

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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

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Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.

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28 September 2017

Expansion of human regulatory T-cells from patients with type 1 diabetes

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RAG2-/- gamma(c)-/- mice transplanted with CD34+ cells from human cord blood show low levels of intestinal engraftment and are resistant to rectal transmission of human immunodeficiency virus

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28 September 2017

Pancreatic islet cell transplant for treatment of diabetes

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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

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28 September 2017

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28 September 2017

Five-year follow-up after clinical islet transplantation

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28 September 2017

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31 May 2018

International trial of the Edmonton protocol for islet transplantation.

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21 January 2018

Amelioration of streptozotocin-induced diabetes in mice using human islet cells derived from long-term culture in vitro

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0090387

21 January 2018

Development of a human adaptive immune system in cord blood cell-transplanted mice

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21 January 2018

Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation

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21 January 2018

Adult porcine islets produce MCP-1 and recruit human monocytes in vitro

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21 January 2018

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

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21 January 2018

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

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21 January 2018

Superantigen-activated regulatory T cells inhibit the migration of innate immune cells and the differentiation of naive T cells.

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21 January 2018

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

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21 January 2018

Redox-regulated mechanisms of IL-4-induced MCP-1 expression in human vascular endothelial cells

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21 January 2018

Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/−Mice

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21 January 2018

Interferon γ: a crucial role in the function of induced regulatory T cells in vivo

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21 January 2018

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28 November 2018

CD4+CD25high regulatory cells in human peripheral blood

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28 November 2018

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24594640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kidney function after islet transplant alone in type 1 diabetes: impact of immunosuppressive therapy on progression of diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24594640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24594640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ CD25+ regulatory T-cells inhibit the islet innate immune response and promote islet engraftment

1 reference

https://pubmed.ncbi.nlm.nih.gov/24594640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0090387

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2014PLoSO...990387X

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24 November 2022

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