Regulatory immune cells in transplantation (Q38013048)

27 August 2017

Regulatory immune cells in transplantation (English)

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27 August 2017

Kathryn J Wood

1

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PubMed ID

22627860

27 August 2017

Andrew Bushell

series ordinal

2

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PubMed ID

22627860

27 August 2017

Joanna Hester

series ordinal

3

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27 August 2017

25 May 2012

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Nature Reviews Immunology

27 August 2017

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27 August 2017

12

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27 August 2017

417-430

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27 August 2017

6

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Mechanisms of rejection: current perspectives.

27 August 2017

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Actively acquired tolerance of foreign cells

21 January 2018

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Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. Mediation of specific suppression by T helper/inducer cells

21 January 2018

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Chimerism and tolerance in a recipient of a deceased-donor liver transplant

21 January 2018

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ABO-incompatible heart transplantation in infants

21 January 2018

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Weaning of immunosuppression in living donor liver transplant recipients

21 January 2018

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Tolerance and chimerism after renal and hematopoietic-cell transplantation

21 January 2018

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HLA-mismatched renal transplantation without maintenance immunosuppression

21 January 2018

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Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation

21 January 2018

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Multiparameter immune profiling of operational tolerance in liver transplantation

21 January 2018

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Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

21 January 2018

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Identification of a B cell signature associated with renal transplant tolerance in humans.

21 January 2018

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Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance

21 January 2018

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Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype.

21 January 2018

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Regulatory T cells in transplantation tolerance

21 January 2018

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FOXP3+ regulatory T cells in the human immune system

21 January 2018

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CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

21 January 2018

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CD8+ regulatory T cells generated by neonatal recognition of peripheral self-antigen

21 January 2018

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CD8+ T suppressor cells and the ILT3 master switch

21 January 2018

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Mechanism and Localization of CD8 Regulatory T Cells in a Heart Transplant Model of Tolerance

21 January 2018

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Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells

21 January 2018

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Double-negative regulatory T cells: non-conventional regulators

21 January 2018

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Immunoregulation in the tissues by gammadelta T cells

21 January 2018

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Control of regulatory T cell lineage commitment and maintenance

21 January 2018

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Allograft rejection mediated by memory T cells is resistant to regulation

21 January 2018

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Chronically rejected rat kidney allografts induce donor-specific tolerance.

21 January 2018

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Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells.

21 January 2018

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Immunologic unresponsiveness to alloantigen in vivo: a role for regulatory T cells

21 January 2018

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Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.

21 January 2018

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Moving to tolerance: clinical application of T regulatory cells

21 January 2018

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Mechanisms of foxp3+ T regulatory cell-mediated suppression

21 January 2018

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Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions

21 January 2018

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CTLA-4-Ig regulates tryptophan catabolism in vivo.

21 January 2018

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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

21 January 2018

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CTLA-4 control over Foxp3+ regulatory T cell function

21 January 2018

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Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance

21 January 2018

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CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner

21 January 2018

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

21 January 2018

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Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

21 January 2018

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Location and time-dependent control of rejection by regulatory T cells culminates in a failure to generate memory T cells

21 January 2018

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Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury.

21 January 2018

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Identification of regulatory T cells in tolerated allografts

21 January 2018

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Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

21 January 2018

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Clinical tolerance in allogeneic hematopoietic stem cell transplantation

21 January 2018

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Suppressor T cells: some answers but more questions

21 January 2018

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Suppressor Cells and Immunoregulation

21 January 2018

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Inhibition of CD40 signaling pathway in antigen presenting cells by T suppressor cells

21 January 2018

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Homeostatic repopulation by CD28-CD8+ T cells in alemtuzumab-depleted kidney transplant recipients treated with reduced immunosuppression

21 January 2018

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Minor H antigen HA-1-specific regulator and effector CD8+ T cells, and HA-1 microchimerism, in allograft tolerance

21 January 2018

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The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo.

21 January 2018

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Inhibition of graft-versus-host disease by double-negative regulatory T cells.

21 January 2018

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Cell therapy with autologous tolerogenic dendritic cells induces allograft tolerance through interferon-gamma and epstein-barr virus-induced gene 3.

21 January 2018

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Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells

21 January 2018

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Natural killer T cells: a bridge to tolerance or a pathway to rejection?

21 January 2018

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Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease

21 January 2018

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Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4-dependent mechanism

21 January 2018

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Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation

21 January 2018

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Regulatory B cells in autoimmunity: developments and controversies.

21 January 2018

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Not always the bad guys: B cells as regulators of autoimmune pathology

21 January 2018

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B cells regulate autoimmunity by provision of IL-10.

21 January 2018

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Prevention of arthritis by interleukin 10-producing B cells

21 January 2018

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CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients

21 January 2018

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Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells

21 January 2018

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CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells

21 January 2018

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Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

21 January 2018

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Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile.

21 January 2018

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CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.

21 January 2018

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Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness.

21 January 2018

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Protective and pathogenic functions of macrophage subsets

21 January 2018

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Regulatory macrophages: setting the threshold for therapy

21 January 2018

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CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

21 January 2018

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Macrophage polarization to a unique phenotype driven by B cells.

21 January 2018

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Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

21 January 2018

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Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

21 January 2018

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Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice

21 January 2018

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Tolerogenic dendritic cells and the quest for transplant tolerance

21 January 2018

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Dendritic cells as a tool to induce transplantation tolerance: obstacles and opportunities

21 January 2018

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Tolerogenic dendritic cells

21 January 2018

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Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes

21 January 2018

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Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients

21 January 2018

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Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo

21 January 2018

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Prolongation of skin graft survival by modulation of the alloimmune response with alternatively activated dendritic cells.

21 January 2018

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Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance

21 January 2018

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Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

21 January 2018

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Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

21 January 2018

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Dendritic cell subset ratio in tolerant, weaning and non-tolerant liver recipients is not affected by extent of immunosuppression

21 January 2018

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High PD-L1/CD86 ratio on plasmacytoid dendritic cells correlates with elevated T-regulatory cells in liver transplant tolerance

21 January 2018

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Tolerogenic plasmacytoid DC.

21 January 2018

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Myeloid-derived suppressor cells: natural regulators for transplant tolerance

21 January 2018

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Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

21 January 2018

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Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice

21 January 2018

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Myeloid-derived suppressor cells protect islet transplants by B7-H1 mediated enhancement of T regulatory cells

21 January 2018

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Mesenchymal stromal cells: facilitators of successful transplantation?

21 January 2018

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Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9

21 January 2018

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Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells.

21 January 2018

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Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population.

21 January 2018

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Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance.

21 January 2018

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Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection

21 January 2018

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Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion

21 January 2018

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A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells

21 January 2018

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Regulatory CD25+ T cells in human kidney transplant recipients.

21 January 2018

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Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

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In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells

21 January 2018

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Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

21 January 2018

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Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.

21 January 2018

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Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

21 January 2018

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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

21 January 2018

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Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells

21 January 2018

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Interleukin-2 and regulatory T cells in graft-versus-host disease

21 January 2018

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The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation

21 January 2018

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Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

21 January 2018

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Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial.

21 January 2018

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Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial

21 January 2018

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Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.

21 January 2018

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Comparative study of clinical grade human tolerogenic dendritic cells

21 January 2018

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Regulatory T cells in stem cell transplantation: strategies and first clinical experiences.

21 January 2018

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Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes.

21 January 2018

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Transplant acceptance-inducing cells as an immune-conditioning therapy in renal transplantation.

21 January 2018

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A cell-based approach to the minimization of immunosuppression in renal transplantation

21 January 2018

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Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression

21 January 2018

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Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development

21 January 2018

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Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells

21 January 2018

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Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo

21 January 2018

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Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF-

21 January 2018

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Suppressor T cells in rats with prolonged cardiac allograft survival after treatment with cyclosporine

21 January 2018

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Mediation of the induction of immunologic unresponsiveness following antigen pretreatment by a CD4 (W3/25+) T cell appearing transiently in the splenic compartment and subsequently in the TDL

31 March 2020

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IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

31 March 2020

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The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

31 March 2020

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Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation

31 March 2020

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Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation

31 March 2020

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Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells

31 March 2020

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Unique patterns of surface receptors, cytokine secretion, and immune functions distinguish T cells in the bone marrow from those in the periphery: impact on allogeneic bone marrow transplantation

31 March 2020

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Evidence that the continued presence of the organ graft and not peripheral donor microchimerism is essential for maintenance of tolerance to alloantigen in vivo in anti-CD4 treated recipients

31 March 2020

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CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection

31 March 2020

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Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance

31 March 2020

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31 March 2020

12 December 2020

Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy

1 reference

Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo.

31 March 2020

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CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses

31 March 2020

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Response to self antigen imprints regulatory memory in tissues

31 March 2020

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Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance

31 March 2020

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Anti-idiotypic network induced by T cell vaccination against experimental autoimmune encephalomyelitis

31 March 2020

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Suppressor T cells in allogeneic models.

31 March 2020

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Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

31 March 2020

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Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation

31 March 2020

1 reference

B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naïve B cells.

31 March 2020

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The significance of non-T-cell pathways in graft rejection: implications for transplant tolerance

31 March 2020

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Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse

31 March 2020

1 reference

Blockade of the CD40-CD40 ligand pathway potentiates the capacity of donor-derived dendritic cell progenitors to induce long-term cardiac allograft survival

31 March 2020

1 reference

Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway

31 March 2020

1 reference

Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion

31 March 2020

1 reference

Endotoxin-induced myeloid-derived suppressor cells inhibit alloimmune responses via heme oxygenase-1

31 March 2020

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Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue

31 March 2020

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GITR ligation blocks allograft protection by induced CD25+CD4+ regulatory T cells without enhancing effector T-cell function

31 March 2020

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Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

31 March 2020

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First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells

31 March 2020

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The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen

31 March 2020

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An investigation to assess the potential of CD25highCD4+ T cells to regulate responses to donor alloantigens in clinically stable renal transplant recipients

31 March 2020

1 reference

12 December 2020

Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells

1 reference

12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

1 reference

12 December 2020

Different subsets of T cells in the adult mouse bone marrow and spleen induce or suppress acute graft-versus-host disease

1 reference

12 December 2020

The role of the CD40 pathway in alloantigen-induced hyporesponsiveness in vivo

1 reference

12 December 2020

Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy.

1 reference

12 December 2020

Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients

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12 December 2020

Identifiers

DOI

10.1038/NRI3227

1 reference

27 August 2017

1 reference

PubMed ID

22627860