The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole (Q27643897)

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Language	Label	Description	Also known as
English	The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole	scientific article

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scholarly article

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The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole (English)

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Haloarcula marismortui

object named as

Haloarcula marismortui

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based on heuristic

inferred from title

author name string

Susan J Schroeder

1

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Gregor Blaha

2

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Julian Tirado-Rives

3

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Thomas A Steitz

4

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Peter B Moore

5

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language of work or name

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publication date

13 April 2007

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Journal of Molecular Biology

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367

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5

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1471-9

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Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

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20 March 2017

Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit

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Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

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The structures of four macrolide antibiotics bound to the large ribosomal subunit

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The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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20 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

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20 March 2017

Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements

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Species-specific antibiotic-ribosome interactions: implications for drug development

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An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

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Structure-activity relationship study on 13-deoxytedanolide, a highly antitumor macrolide from the marine sponge Mycale adhaerens.

1 reference

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Antibiotics acting on the translational machinery

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Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA.

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Antibiotics targeting ribosomes: crystallographic studies

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Drastic alteration of cycloheximide sensitivity by substitution of one amino acid in the L41 ribosomal protein of yeasts

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1 reference

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13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit

1 reference

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The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit

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Mode of action of the antitumor compound girodazole (RP 49532A, NSC 627434)

1 reference

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based on heuristic

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Modified ribosomes conferring resistance to cycloheximide in mutants of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17321546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2007.01.081

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