Structural basis for autoinhibition of Notch (Q27644319)

2

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Gavin Histen

3

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Cheryll Sanchez-Irizarry

4

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Jon C Aster

5

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Stephen C Blacklow

Nature Structural & Molecular Biology

6

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publication date

April 2007

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published in

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volume

14

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page(s)

295-300

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issue

4

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cites work

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

1 reference

The Notch1 receptor is cleaved constitutively by a furin-like convertase

21 April 2017

1 reference

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 April 2017

1 reference

Nuclear access and action of notch in vivo

21 April 2017

1 reference

Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1

21 April 2017

1 reference

Mapping the protein universe

21 April 2017

1 reference

Notch signaling: from the outside in

21 April 2017

1 reference

Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta

21 April 2017

1 reference

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

21 April 2017

1 reference

Automated protein model building combined with iterative structure refinement

21 April 2017

1 reference

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 April 2017

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

21 April 2017

1 reference

Notch signalling: a simple pathway becomes complex

21 April 2017

1 reference

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 April 2017

1 reference

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

21 April 2017

1 reference

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

21 January 2018

1 reference

The ins and outs of notch signaling

21 January 2018

1 reference

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

21 January 2018

1 reference

A common enzyme connects notch signaling and Alzheimer's disease

21 January 2018

1 reference

Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo

21 January 2018

1 reference

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

21 January 2018

1 reference

Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.

21 January 2018

1 reference

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans.

21 January 2018

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Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin

21 January 2018

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The roles of receptor and ligand endocytosis in regulating Notch signaling

21 January 2018

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Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

21 January 2018

1 reference

Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.

21 January 2018

1 reference

Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain

21 January 2018

1 reference

The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta

21 January 2018

1 reference

Unequal segregation of Neuralized biases Notch activation during asymmetric cell division.

21 January 2018

1 reference

neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

21 January 2018

1 reference

Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

21 January 2018

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The adhesion force of Notch with Delta and the rate of Notch signaling

21 January 2018

1 reference

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins

21 January 2018

1 reference

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

21 January 2018

1 reference

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

21 January 2018

1 reference

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei

31 March 2020

1 reference

Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)

31 March 2020

1 reference

Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila

31 March 2020

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB1227

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1357891

1014955709

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Fatcat ID

release_pxugl77bubgrxphpygsmx5lhsq

0 references

1357891

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference