Structural basis of substrate specificity in the serine proteases (Q29619675)

Europe PubMed Central

title

Structural basis of substrate specificity in the serine proteases (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7795518

30 April 2017

author name string

Perona JJ

series ordinal

1

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30 April 2017

Craik CS

series ordinal

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7795518

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language of work or name

1 reference

30 April 2017

publication date

March 1995

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volume

4

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page(s)

337-60

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issue

3

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Relocating a negative charge in the binding pocket of trypsin

30 April 2017

cites work

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Structure of an engineered, metal-actuated switch in trypsin

30 April 2017

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Structure of human des(1-45) factor Xa at 2.2 A resolution

30 April 2017

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Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution

30 April 2017

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Structure of human factor D. A complement system protein at 2.0 A resolution

30 April 2017

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Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase

30 April 2017

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PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

30 April 2017

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A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding

30 April 2017

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Crystal structure of a catalytic antibody with a serine protease active site

30 April 2017

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Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI

30 April 2017

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

30 April 2017

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Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin

30 April 2017

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The preparation and properties of the catalytic subunit of bovine enterokinase

30 April 2017

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The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor

30 April 2017

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On the size of the active site in proteases. I. Papain

30 April 2017

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Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

30 April 2017

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Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure

30 April 2017

1 reference

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Electron density calculations as an extension of protein structure refinement. Streptomyces griseus protease A at 1.5 A resolution

30 April 2017

1 reference

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Site-directed mutagenesis and the role of the oxyanion hole in subtilisin

30 April 2017

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Crystal structure of trp repressor/operator complex at atomic resolution

30 April 2017

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The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor

30 April 2017

1 reference

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Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases

30 April 2017

1 reference

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Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes

30 April 2017

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The structure of rat mast cell protease II at 1.9-A resolution

30 April 2017

1 reference

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Refined crystal structure of Streptomyces griseus trypsin at 1.7 A resolution

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid

30 April 2017

1 reference

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The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis

30 April 2017

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Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo

30 April 2017

1 reference

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Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution

30 April 2017

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Structural plasticity broadens the specificity of an engineered protease

30 April 2017

1 reference

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Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content

30 April 2017

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How do serine proteases really work?

30 April 2017

1 reference

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Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

30 April 2017

1 reference

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Crystal structures of two engineered thiol trypsins

30 April 2017

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Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates

30 April 2017

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The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

30 April 2017

1 reference

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Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Substrate specificity of trypsin investigated by using a genetic selection

30 April 2017

1 reference

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Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

30 April 2017

1 reference

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Structural basis for broad specificity in alpha-lytic protease mutants

30 April 2017

1 reference

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The coagulation cascade: initiation, maintenance, and regulation

30 April 2017

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Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor)

30 April 2017

1 reference

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Crystal structure of the alkaline proteinase Savinase™ from Bacillus lentus at 1.4 Å resolution

30 April 2017

1 reference

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Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease

30 April 2017

1 reference

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The alpha/beta hydrolase fold

30 April 2017

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Refined atomic model of wheat serine carboxypeptidase II at 2.2-A resolution

30 April 2017

1 reference

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Serine Proteases: Structure and Mechanism of Catalysis

30 April 2017

1 reference

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Random mutagenesis of the substrate-binding site of a serine protease can generate enzymes with increased activities and altered primary specificities

30 April 2017

1 reference

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Trypsin display on the surface of bacteriophage

3 June 2018

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Substrate phage: selection of protease substrates by monovalent phage display

3 June 2018

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Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles

3 June 2018

1 reference

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Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

3 June 2018

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Thrombin-variable region 1 (VR1). Evidence for the dominant contribution of VR1 of serine proteases to their interaction with plasminogen activator inhibitor 1.

3 June 2018

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Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis.

3 June 2018

1 reference

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Mutagenesis supports water mediated recognition in the trp repressor-operator system.

3 June 2018

1 reference

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A genetic selection elucidates structural determinants of arginine versus lysine specificity in trypsin

3 June 2018

1 reference

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Role of the S' subsites in serine protease catalysis. Active-site mapping of rat chymotrypsin, rat trypsin, alpha-lytic protease, and cercarial protease from Schistosoma mansoni.

3 June 2018

1 reference

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Determinants of repressor/operator recognition from the structure of the trp operator binding site.

3 June 2018

1 reference

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Protein folding: predicting predicting

3 June 2018

1 reference

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Conversion of the substrate specificity of mouse proteinase granzyme B.

3 June 2018

1 reference

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Crystallographic and NMR studies of the serine proteases

3 June 2018

1 reference

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Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin

3 June 2018

1 reference

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Evolution of Proteolytic Enzymes

3 June 2018

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Proteases and posttranslational processing of prohormones: a review

3 June 2018

1 reference

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Evidence for an extended active center in elastase

3 June 2018

1 reference

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A family of protein-cutting proteins.

3 June 2018

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Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region

3 June 2018

1 reference

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3 June 2018

1 reference

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Primary structure of human neutrophil elastase

3 June 2018

1 reference

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Designing substrate specificity by protein engineering of electrostatic interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells

3 June 2018

1 reference

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Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes

3 June 2018

1 reference

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Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering

3 June 2018

1 reference

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Dissecting the catalytic triad of a serine protease

3 June 2018

1 reference

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Subtilisin--an enzyme designed to be engineered

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Electrostatic complementarity within the substrate-binding pocket of trypsin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors

3 June 2018

1 reference

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Introduction of a cysteine protease active site into trypsin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Engineering subtilisin BPN' for site-specific proteolysis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The role of easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Functional interaction among catalytic residues in subtilisin BPN'.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Regulation of serine protease activity by an engineered metal switch

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Crystallographic analysis of trypsin-G226A. A specificity pocket mutant of rat trypsin with altered binding and catalysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

pH-dependent mechanism in the catalysis of prolyl endopeptidase from pig muscle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The primary structure of the glutamic acid-specific protease of Streptomyces griseus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Free energy calculations on binding and catalysis by alpha-lytic protease: the role of substrate size in the P1 pocket

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Computational method for the design of enzymes with altered substrate specificity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Mammalian Neural and Endocrine Pro-Protein and Pro-Hormone Convertases Belonging to the Subtilisin Family of Serine Proteinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Mutational remodeling of enzyme specificity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Converting trypsin to chymotrypsin: the role of surface loops

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Molecular cloning of a cDNA that encodes a serine protease with chymotryptic and collagenolytic activities in the hepatopancreas of the shrimp Penaeus vanameii (Crustacea, Decapoda)

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The active centers of Streptomyces griseus protease 3 and alpha-chymotrypsin: enzyme-substrate interactions remote from the scissile bond

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Active centers of Streptomyces griseus protease 1, Streptomyces griseus protease 3, and α-chymotrypsin: enzyme-substrate interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Immunofluorescent localization of a serine protease in rat small intestine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The apparent molecular weights of human intestinal aminopeptidase, enterokinase and maltase in native duodenal fluid

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The 2.8 Å resolution structure of Streptomyces griseus protease B and its homology with α-chymotrypsin and Streptomyces griseus protease A

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

A major serine protease in rat skeletal muscle: Evidence for its mast cell origin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The primary structure of staphylococcal protease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Mutational replacements in subtilisin 309. Val104 has a modulating effect on the P4 substrate preference

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

On the evolution of specificity and catalysis in subtilisin

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FPRO.5560040301

Probing steric and hydrophobic effects on enzyme-substrate interactions by protein engineering.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Long-range surface charge-charge interactions in proteins. Comparison of experimental results with calculations from a theoretical method.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Autocatalytic maturation of the prohormone convertase PC2.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Ventralizing signal determined by protease activation in Drosophila embryogenesis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Exogenous acetate reconstitutes the enzymatic activity of trypsin Asp189Ser

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

The substrate specificity of Uca pugilator collagenolytic serine protease 1 correlates with the bovine type I collagen cleavage sites.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Structural origins of substrate discrimination in trypsin and chymotrypsin

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II. Bovine chymotrypsin A alpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester s

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Electrostatic effects on modification of charged groups in the active site cleft of subtilisin by protein engineering

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Engineering enzyme specificity by "substrate-assisted catalysis"

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Why ion pair reversal by protein engineering is unlikely to succeed

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Comparative modeling methods: application to the family of the mammalian serine proteases

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143081

Purification and Specificity of Porcine Enterokinase

26 November 2018

1 reference

12 December 2020

Three-dimensional Fourier Synthesis of Tosyl-elastase at 3.5 Å Resolution

1 reference

12 December 2020

Free energy perturbation calculations on binding and catalysis after mutating threonine 220 in subtilisin

1 reference

12 December 2020

Amino acid sequence of a collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator

1 reference

12 December 2020

Active site of alpha-lytic protease: enzyme-substrate interactions

1 reference

12 December 2020

Peptides combined with 14C-diisopropyl phosphoryl following degradation of 14C-DIP-trypsin with alpha-chymotrypsin

1 reference

12 December 2020

Contribution of long-range electrostatic interactions to the stabilization of the catalytic transition state of the serine protease subtilisin BPN'

1 reference

12 December 2020

Probing the mechanism and improving the rate of substrate-assisted catalysis in subtilisin BPN'

1 reference

12 December 2020

Significance of hydrophobic S4-P4 interactions in subtilisin 309 from Bacillus lentus

1 reference

12 December 2020

Structure of wheat serine carboxypeptidase II at 3.5-A resolution. A new class of serine proteinase

1 reference

12 December 2020

Engineering a novel specificity in subtilisin BPN'

1 reference

12 December 2020

Three-dimensional structure of proteinase K at 0.15-nm resolution

1 reference

12 December 2020

Catalysis by human leukocyte elastase: proton inventory as a mechanistic probe

1 reference

12 December 2020

Engineering of the substrate-binding region of the subtilisin-like, cell-envelope proteinase of Lactococcus lactis

1 reference

12 December 2020

Structure of Subtilisin BPN′ at 2.5 Å Resolution

1 reference

12 December 2020

Variants of subtilisin BPN' with altered specificity profiles

1 reference

12 December 2020

Protein engineering of the high-alkaline serine protease PB92 from Bacillus alcalophilus: functional and structural consequences of mutation at the S4 substrate binding pocket

1 reference

12 December 2020

Redesigning trypsin: alteration of substrate specificity

1 reference

12 December 2020

Free energy perturbation calculations on binding and catalysis after mutating Asn 155 in subtilisin

1 reference

12 December 2020

Interdependency of the binding subsites in subtilisin

1 reference

12 December 2020

A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues

1 reference

12 December 2020

Subtilisin. Stereochemical mechanism involving transition-state stabilization

1 reference

12 December 2020

The epidermolytic toxins are serine proteases

1 reference

12 December 2020

Substrate specificity of two chymotrypsin-like proteases from rat mast cells. Studies with peptide 4-nitroanilides and comparison with cathepsin G

1 reference

12 December 2020

Polypeptide halomethyl ketones bind to serine proteases as analogs of the tetrahedral intermediate. X-ray crystallographic comparison of lysine- and phenylalanine-polypeptide chloromethyl ketone-inhibited subtilisin

1 reference

12 December 2020

Free energy calculations by computer simulation

1 reference

12 December 2020

Three-dimensional Structure of Tosyl-α-chymotrypsin

1 reference

12 December 2020

Amino acid sequence of rat mast cell protease I (chymase)

1 reference

12 December 2020

Site-directed mutagenesis on (serine) carboxypeptidase Y. A hydrogen bond network stabilizes the transition state by interaction with the C-terminal carboxylate group of the substrate

1 reference

12 December 2020

An x-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'

1 reference

12 December 2020

The catalytic role of the active site aspartic acid in serine proteases

1 reference

12 December 2020

Hydrolysis of small peptide substrates parallels binding of chymotrypsin inhibitor 2 for mutants of subtilisin BPN'

1 reference

12 December 2020

Extensive comparison of the substrate preferences of two subtilisins as determined with peptide substrates which are based on the principle of intramolecular quenching

1 reference

12 December 2020

Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity

1 reference

12 December 2020

Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with noncollagenous substrates

1 reference

12 December 2020

Mutational replacements of the amino acid residues forming the hydrophobic S4 binding pocket of subtilisin 309 from Bacillus lentus

1 reference

12 December 2020

Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids

1 reference

12 December 2020

Identifiers

DOI

10.1002/PRO.5560040301

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7795518

30 April 2017

793270

793270

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7795518

2 references

30 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7795518

2 references

30 April 2017