A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain (Q27646868)

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English	A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain	scientific article

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scholarly article

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A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain (English)

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Thomas P Sakmar

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Thomas P Sakmar

2

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author name string

Jay M Janz

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K Christopher Min

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language of work or name

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publication date

28 September 2007

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Journal of Biological Chemistry

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282

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39

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28893-903

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Activated Cdc42 Sequesters c-Cbl and Prevents EGF Receptor Degradation

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The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

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Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

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Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

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BetaPix-a enhances the activity of phospholipase Cgamma1 by binding SH3 domain in breast cancer

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Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix

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Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix

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WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation

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Identifiers

10.1074/JBC.M702678200

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