High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL (Q27653863)

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21 January 2020

title

High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL (English)

1 reference

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21 January 2020

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21 January 2020

Brian J. Smith

3

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21 January 2020

Walter D Fairlie

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21 January 2020

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Peter E Czabotar

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21 January 2020

2

Jack D Sadowsky

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Kimberly J Peterson-Kaufman

21 January 2020

5

object named as

Kimberly J Peterson-Kaufman

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21 January 2020

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Samuel H Gellman

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21 January 2020

author name string

Peter M Colman

6

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21 January 2020

language of work or name

English

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publication date

1 January 2009

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Angewandte Chemie International Edition

21 January 2020

published in

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21 January 2020

volume

48

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21 January 2020

issue

24

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21 January 2020

page(s)

4318-4322

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Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly

21 January 2020

cites work

1 reference

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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

20 March 2017

1 reference

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A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

20 March 2017

1 reference

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Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

20 March 2017

1 reference

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

20 March 2017

1 reference

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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

20 March 2017

1 reference

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Bcl-XL Mutations Suppress Cellular Sensitivity to Antimycin A

20 March 2017

1 reference

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The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

20 March 2017

1 reference

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

20 March 2017

1 reference

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Foldamers as versatile frameworks for the design and evolution of function

20 March 2017

1 reference

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

20 March 2017

1 reference

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The Bcl2 family: regulators of the cellular life-or-death switch

7 April 2017

1 reference

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BCL-2 family antagonists for cancer therapy

7 April 2017

1 reference

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Foldamers with heterogeneous backbones

29 September 2017

1 reference

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Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL.

29 September 2017

1 reference

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Inhibiting HIV fusion with a beta-peptide foldamer

29 September 2017

1 reference

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Structural biology of the Bcl-2 family of proteins

29 September 2017

1 reference

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beta-Peptides: from structure to function

29 September 2017

1 reference

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Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains.

29 September 2017

1 reference

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Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.

2 June 2018

1 reference

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Rational development of beta-peptide inhibitors of human cytomegalovirus entry

2 June 2018

1 reference

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Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation

2 June 2018

1 reference

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Helical beta-peptide inhibitors of the p53-hDM2 interaction.

27 November 2018

1 reference

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Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition

27 November 2018

1 reference

12 December 2020

Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence

1 reference

12 December 2020

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions

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12 December 2020

Crystallographic characterization of the alpha/beta-peptide 14/15-helix

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANIE.200805761

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4259188

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19229915%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

21 January 2020

4259188

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19229915%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

19229915

1 reference