A De Novo Protein Binding Pair By Computational Design and Directed Evolution (Q27667402)

12

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Jacob E Corn

object named as

Jacob E Corn

2

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David Baker

object named as

David Baker

15

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author name string

John Karanicolas

1

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Irwin Chen

3

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Lukasz A Joachimiak

4

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Orly Dym

5

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Sun H Peck

6

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Shira Albeck

7

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Tamar Unger

8

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Wenxin Hu

9

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Gaohua Liu

10

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Scott Delbecq

11

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Clint P Spiegel

13

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David R Liu

A Synthetic Coiled-Coil Interactome Provides Heterospecific Modules for Molecular Engineering

14

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publication date

22 April 2011

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published in

Molecular Cell

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volume

42

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page(s)

250-60

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issue

2

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cites work

1 reference

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

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A hot spot of binding energy in a hormone-receptor interface

20 March 2017

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7 April 2017

1 reference

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7 April 2017

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Backbone flexibility in computational protein design

29 September 2017

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29 September 2017

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Design of protein-interaction specificity gives selective bZIP-binding peptides.

29 September 2017

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Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions

29 September 2017

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Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display

29 September 2017

1 reference

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Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling

29 September 2017

1 reference

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Predicting helix orientation for coiled-coil dimers

29 September 2017

1 reference

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A de novo designed protein protein interface

29 September 2017

1 reference

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Enzyme promiscuity: evolutionary and mechanistic aspects.

29 September 2017

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Evolution of hormone-receptor complexity by molecular exploitation

29 September 2017

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Effects of interface mutations on association modes and electron-transfer rates between proteins

29 September 2017

1 reference

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Conservation and relative importance of residues across protein-protein interfaces

29 September 2017

1 reference

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Engineering novel binding proteins from nonimmunoglobulin domains

29 September 2017

1 reference

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Allosteric inhibition of aminoglycoside phosphotransferase by a designed ankyrin repeat protein

29 September 2017

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In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved

29 September 2017

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Anchor residues in protein-protein interactions

29 September 2017

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A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins

29 September 2017

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Directed evolution of high-affinity antibody mimics using mRNA display

29 September 2017

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An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues

29 September 2017

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Optimizing protein stability in vivo

29 September 2017

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Characterizing dynamic protein-protein interactions using differentially scaled paramagnetic relaxation enhancement

2 June 2018

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RosettaHoles: rapid assessment of protein core packing for structure prediction, refinement, design, and validation

2 June 2018

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Realistic protein-protein association rates from a simple diffusional model neglecting long-range interactions, free energy barriers, and landscape ruggedness

2 June 2018

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Funnel hunting in a rough terrain: learning and discriminating native energy funnels.

2 June 2018

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Computational alanine scanning mutagenesis--an improved methodological approach

27 November 2018

1 reference

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Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR.

27 November 2018

1 reference

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Structure-based prediction of bZIP partnering specificity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102007

Protein-protein interactions: hot spots and structurally conserved residues often locate in complemented pockets that pre-organized in the unbound states: implications for docking.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102007

Computational redesign of protein-protein interaction specificity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102007

Taking geometry to its edge: fast unbound rigid (and hinge-bent) docking.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102007

Modulating calmodulin binding specificity through computational protein design

27 November 2018

1 reference

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Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21458342

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Relationship Between Sequence and Interaction Divergence in Proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21458342

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2011.03.010

1 reference

2021494

2021494

1 reference

1 reference

1 reference