Structural basis for compound C inhibition of the human AMP-activated protein kinase α2 subunit kinase domain (Q27667722)

ChEBI release 2020-05-28

8

0 references

Seiichiro Kishishita

4

Seiichiro Kishishita

0 references

Shigeyuki Yokoyama

Shigeyuki Yokoyama

16

0 references

Yasuhiko Minokoshi

Yasuhiko Minokoshi

15

0 references

Shinya Saijo

3

Shinya Saijo

0 references

Mitsutoshi Toyama

6

Mitsutoshi Toyama

0 references

Takaho Terada

7

Takaho Terada

0 references

Tetsuo Takagi

2

Tetsuo Takagi

0 references

Daisuke Takaya

5

Daisuke Takaya

0 references

Noriko Handa

1

Noriko Handa

0 references

Toshimasa Yamauchi

11

Toshimasa Yamauchi

0 references

Miki Okada-Iwabu

12

Miki Okada-Iwabu

0 references

Masato Iwabu

13

Masato Iwabu

0 references

author name string

Atsushi Suzuki

9

0 references

Suni Lee

10

0 references

Takashi Kadowaki

Acta Crystallographica Section D: Biological Crystallography

14

0 references

language of work or name

1 reference

May 2011

0 references

published in

0 references

volume

67

0 references

issue

Pt 5

0 references

page(s)

480-7

0 references

cites work

Structure of mammalian AMPK and its regulation by ADP

1 reference

https://api.crossref.org/works/10.1107/S0907444911010201

LKB1-dependent signaling pathways

21 April 2017

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Structural insight into the autoinhibition mechanism of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

ESPript: analysis of multiple sequence alignments in PostScript

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

AMP-activated protein kinase--development of the energy sensor concept.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Structural insight into AMPK regulation: ADP comes into play

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Preparation of Escherichia coli cell extract for highly productive cell-free protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

An inhibited conformation for the protein kinase domain of theSaccharomyces cerevisiaeAMPK homolog Snf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Molecular replacement with MOLREP

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Structural basis for AMP binding to mammalian AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201

Cell-free production and stable-isotope labeling of milligram quantities of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911010201