Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function (Q27673761)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023261%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function (English)

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9 March 2020

0 references

3

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9 March 2020

Christopher W Murray

8

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9 March 2020

author name string

Susanne M Saalau-Bethell

1

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9 March 2020

Andrew J Woodhead

2

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9 March 2020

Maria G Carr

4

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9 March 2020

Joseph Coyle

5

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9 March 2020

Brent Graham

6

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9 March 2020

Steven D Hiscock

7

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9 March 2020

Puja Pathuri

9

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9 March 2020

Sharna J Rich

10

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9 March 2020

Caroline J Richardson

11

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9 March 2020

Pamela A Williams

12

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9 March 2020

Harren Jhoti

13

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9 March 2020

publication date

30 September 2012

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9 March 2020

published in

Nature Chemical Biology

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9 March 2020

volume

8

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9 March 2020

issue

11

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page(s)

920-925

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

9 March 2020

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20 March 2017

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20 March 2017

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Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase

20 March 2017

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The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase

20 March 2017

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20 March 2017

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

20 March 2017

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Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells

20 March 2017

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Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors

20 March 2017

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Integration, scaling, space-group assignment and post-refinement

20 March 2017

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20 March 2017

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20 March 2017

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

20 March 2017

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The design of drugs for HIV and HCV

20 March 2017

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20 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate

2 June 2018

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Use of the fused NS4A peptide-NS3 protease domain to study the importance of the helicase domain for protease inhibitor binding to hepatitis C virus NS3-NS4A.

21 January 2018

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Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.

21 January 2018

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The impact of drug resistance on the effectiveness of chemotherapy for chronic hepatitis B.

21 January 2018

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The Los Alamos hepatitis C sequence database

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.1081

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023261%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 March 2020

1037343584

0 references

1 reference

2 references

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9 March 2020

2 references

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