Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor (Q27676453)

10

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Andreas Koeberle

4

object named as

Andreas Koeberle

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Oliver Werz

8

object named as

Oliver Werz

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author name string

Solveigh C Koeberle

1

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Johannes Romir

2

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Stefan Fischer

3

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Verena Schattel

5

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Wolfgang Albrecht

6

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Christian Grütter

7

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Daniel Rauh

9

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Stefan A Laufer

Macrophage migration inhibitory factor elicits an angiogenic phenotype in human ectopic endometrial cells and triggers the production of major angiogenic factors via CD44, CD74, and MAPK signaling pathways

11

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publication date

25 December 2011

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published in

Nature Chemical Biology

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volume

8

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issue

2

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page(s)

141-3

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cites work

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Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity

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The protein kinase complement of the human genome

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Signal integration by JNK and p38 MAPK pathways in cancer development

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Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

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MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein

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Aza-analogue dibenzepinone scaffolds as p38 mitogen-activated protein kinase inhibitors: design, synthesis, and biological data of inhibitors with improved physicochemical properties

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Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase

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Hyperosmolar sodium chloride, p38 mitogen activated protein and cytokine-mediated inflammation

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The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis

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Interleukin (IL)-4 and IL-13 up-regulate monocyte chemoattractant protein-1 expression in human bronchial epithelial cells: involvement of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2 and Janus kinase-2 but not c-J

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The Mycobacterium tuberculosis early secreted antigenic target of 6 kDa inhibits T cell interferon-γ production through the p38 mitogen-activated protein kinase pathway

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The p38alpha kinase plays a central role in inflammation

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Rho kinase-2 activation in human endothelial cells drives lysophosphatidic acid-mediated expression of cell adhesion molecules via NF-kappaB p65.

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Interleukin-3, -5, and granulocyte macrophage colony-stimulating factor induce adhesion and chemotaxis of human eosinophils via p38 mitogen-activated protein kinase and nuclear factor kappaB.

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Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10.

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Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A.

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αVβ3-integrin expression through ERK activation mediates cell attachment and is necessary for production of tumor necrosis factor alpha in monocytic THP-1 cells stimulated by phorbol myristate acetate

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Design, synthesis, and biological evaluation of phenylamino-substituted 6,11-dihydro-dibenzo[b,e]oxepin-11-ones and dibenzo[a,d]cycloheptan-5-ones: novel p38 MAP kinase inhibitors

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22198732

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesion

1 reference

PubMed

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