A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating Domain (Q27681733)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24530065%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain (English)

1 reference

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8 March 2020

0 references

0 references

4

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8 March 2020

Zoltan Dekan

6

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8 March 2020

Mehdi Mobli

7

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8 March 2020

Norelle L Daly

8

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8 March 2020

Paul F Alewood

9

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8 March 2020

Laurie L Parker

10

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Glenn F King

11

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8 March 2020

5

Minervo Perez

1 reference

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8 March 2020

author name string

Junhong Gui

1

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8 March 2020

Boyi Liu

2

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8 March 2020

Guan Cao

3

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Yufeng Zhou

12

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8 March 2020

Sven-Eric Jordt

13

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8 March 2020

Michael N Nitabach

14

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language of work or name

English

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publication date

13 February 2014

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8 March 2020

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8 March 2020

volume

24

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issue

5

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8 March 2020

page(s)

473-483

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International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family

8 March 2020

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The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider

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ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

20 March 2017

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TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury

20 March 2017

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TRPA1 is a major oxidant sensor in murine airway sensory neurons

20 March 2017

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Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

20 March 2017

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TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

20 March 2017

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Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing

20 March 2017

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Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

20 March 2017

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TRPA1 antagonists as potential analgesic drugs.

7 April 2017

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Venoms as a platform for human drugs: translating toxins into therapeutics

29 September 2017

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Use of venom peptides to probe ion channel structure and function

29 September 2017

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TRPA1 modulators in preclinical development

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29 September 2017

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Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.

29 September 2017

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Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels

29 September 2017

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29 September 2017

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Deconstructing voltage sensor function and pharmacology in sodium channels

29 September 2017

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Phase coupling of a circadian neuropeptide with rest/activity rhythms detected using a membrane-tethered spider toxin

29 September 2017

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HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

29 September 2017

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Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels

29 September 2017

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Transcriptome analysis revealed novel possible venom components and cellular processes of the tarantula Chilobrachys jingzhao venom gland

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function

29 September 2017

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Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

29 September 2017

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Membrane potential-dependent binding of scorpion toxin to the action potential Na+ ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination

29 September 2017

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Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

29 September 2017

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Transient receptor potential A1 and cannabinoid receptor activity in human normal and hyperplastic prostate: relation to nerves and interstitial cells

2 June 2018

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Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.

2 June 2018

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A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.

2 June 2018

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Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels.

2 June 2018

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Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites.

2 June 2018

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Tarantula toxin ProTx-I differentiates between human T-type voltage-gated Ca2+ Channels Cav3.1 and Cav3.2.

2 June 2018

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The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation.

27 November 2018

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Molecular diversity and evolution of cystine knot toxins of the tarantula Chilobrachys jingzhao

27 November 2018

1 reference

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Differential expression profile of cold (TRPA1) and cool (TRPM8) receptors in human urogenital organs

27 November 2018

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Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.

27 November 2018

1 reference

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Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole

27 November 2018

1 reference

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Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder

27 November 2018

1 reference

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TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949122

Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels

27 November 2018

1 reference

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Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24530065

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TRP channels in disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24530065

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CUB.2014.01.013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24530065%20AND%20SRC:MED&resulttype=core&format=json

release_unuhmlewunbednq2cqk75z6s6i

8 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/unuhmlewunbednq2cqk75z6s6i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24530065%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24530065%20AND%20SRC:MED&resulttype=core&format=json