Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones (Q27683870)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847884%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones (English)

1 reference

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18 March 2020

1 reference

7

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18 March 2020

Markus A Seeliger

9

1 reference

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18 March 2020

8

Maureen J Charron

1 reference

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18 March 2020

author name string

Juan Pablo Maianti

1

1 reference

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18 March 2020

Amanda McFedries

2

1 reference

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18 March 2020

Zachariah H Foda

3

1 reference

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18 March 2020

Ralph E Kleiner

4

1 reference

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18 March 2020

Xiu Quan Du

5

1 reference

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18 March 2020

Malcolm A Leissring

6

1 reference

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18 March 2020

Alan Saghatelian

10

1 reference

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18 March 2020

David R Liu

11

1 reference

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18 March 2020

language of work or name

English

0 references

publication date

21 May 2014

1 reference

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18 March 2020

1 reference

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18 March 2020

volume

511

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18 March 2020

page(s)

94-98

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18 March 2020

issue

7507

1 reference

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Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

18 March 2020

cites work

1 reference

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Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

20 March 2017

1 reference

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Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme †

20 March 2017

1 reference

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Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

20 March 2017

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DNA-templated organic synthesis and selection of a library of macrocycles

20 March 2017

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

20 March 2017

1 reference

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The inactivation of insulin by tissue extracts; the distribution and properties of insulin inactivating extracts

20 March 2017

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A genome-wide association study identifies novel risk loci for type 2 diabetes

20 March 2017

1 reference

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Insulin degradation: progress and potential

20 March 2017

1 reference

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Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

20 March 2017

1 reference

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

20 March 2017

1 reference

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Emerging combinatorial hormone therapies for the treatment of obesity and T2DM.

20 March 2017

1 reference

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Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides.

29 September 2017

1 reference

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Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142213

Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance

29 September 2017

1 reference

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Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142213

Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin

29 September 2017

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29 September 2017

1 reference

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The biology of incretin hormones

29 September 2017

1 reference

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Effects on plasma glucose and lactate

29 September 2017

1 reference

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Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1.

29 September 2017

1 reference

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The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes

29 September 2017

1 reference

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Insulin and Glucagon Degradation by the Same Enzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142213

Evaluating the glucose tolerance test in mice

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13297

The augmenting effect on insulin secretion by oral versus intravenous glucose is exaggerated by high-fat diet in mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13297

Drug therapy of postprandial hyperglycaemia.

21 January 2018

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Degradation of amylin by insulin-degrading enzyme

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24847884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of endogenous amylin in glucagon secretion and gastric emptying in rats demonstrated with the selective antagonist, AC187

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24847884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847884%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 March 2020

0 references

1 reference

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18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847884%20AND%20SRC:MED&resulttype=core&format=json