Crystal structure of NLRC4 reveals its autoinhibition mechanism (Q27684807)

NLR family, CARD domain containing 4

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Zehan Hu

1

1 reference

ORCID Public Data File 2021

author name string

Chuangye Yan

2

0 references

Peiyuan Liu

3

0 references

Zhiwei Huang

4

0 references

Rui Ma

5

0 references

Chenlu Zhang

6

0 references

Ruiyong Wang

7

0 references

Yueteng Zhang

8

0 references

Fabio Martinon

9

0 references

Di Miao

10

0 references

Haiteng Deng

11

0 references

Jiawei Wang

12

0 references

Junbiao Chang

13

0 references

Jijie Chai

Regulation of inflammasome signaling

14

0 references

language of work or name

English

0 references

publication date

12 July 2013

0 references

published in

Science

0 references

volume

341

0 references

issue

6142

0 references

page(s)

172-5

0 references

cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Phosphorylation of NLRC4 is critical for inflammasome activation

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Structure of the apoptotic protease-activating factor 1 bound to ADP

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Structure of the Drosophila Apoptosome at 6.9 Å Resolution

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

The Nod-like receptor (NLR) family: a tale of similarities and differences

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Automated MAD and MIR structure solution

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Maximum-likelihood density modification

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

A structural basis of the interactions between leucine-rich repeats and protein ligands

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

Phasercrystallographic software

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1236381

PHENIX: building new software for automated crystallographic structure determination

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Inflammasomes in health and disease

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Evolutionary relationships and structural mechanisms of AAA+ proteins

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Recognition of bacteria by inflammasomes

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Sensing and reacting to microbes through the inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Policing the cytosol--bacterial-sensing inflammasome receptors and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Inflammasomes in carcinogenesis and anticancer immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Wheel of Life, Wheel of Death: A Mechanistic Insight into Signaling by STAND Proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Changes in Apaf-1 Conformation That Drive Apoptosome Assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Multistate folding of a hyperthermostable Fe-superoxide dismutase (TcSOD) in guanidinium hydrochloride: The importance of the quaternary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

A new model for the transition of APAF-1 from inactive monomer to caspase-activating apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Expression, glycosylation, and phosphorylation of human keratins 8 and 18 in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381

Immunology. Orchestrating inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1236381