Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain (Q27694576)

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10 March 2020

title

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain (English)

1 reference

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G protein-coupled receptor

10 March 2020

main subject

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transmembrane protein

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author

Fiona H. Marshall

13

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10 March 2020

author name string

Andrew S Doré

1

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10 March 2020

Krzysztof Okrasa

2

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10 March 2020

Jayesh C Patel

3

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10 March 2020

Maria Serrano-Vega

4

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10 March 2020

Kirstie Bennett

5

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10 March 2020

Robert M Cooke

6

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10 March 2020

James C Errey

7

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10 March 2020

Ali Jazayeri

8

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10 March 2020

Samir Khan

9

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10 March 2020

Ben Tehan

10

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10 March 2020

Malcolm Weir

11

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10 March 2020

Giselle R Wiggin

12

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10 March 2020

language of work or name

English

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publication date

6 July 2014

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10 March 2020

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10 March 2020

volume

511

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10 March 2020

issue

7511

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10 March 2020

page(s)

557-562

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Diversity and modularity of G protein-coupled receptor structures

10 March 2020

cites work

1 reference

Structure of the human smoothened receptor bound to an antitumour agent

21 April 2017

1 reference

Structure of class B GPCR corticotropin-releasing factor receptor 1

21 April 2017

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Structure of the human glucagon class B G-protein-coupled receptor

21 April 2017

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

21 April 2017

1 reference

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

21 April 2017

1 reference

Protein homology detection by HMM-HMM comparison

21 April 2017

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Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling

21 April 2017

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Crystal structure of opsin in its G-protein-interacting conformation

21 April 2017

1 reference

Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 April 2017

1 reference

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

21 April 2017

1 reference

21 April 2017

1 reference

Overview of the CCP4 suite and current developments

21 April 2017

1 reference

Phasercrystallographic software

21 April 2017

1 reference

REFMAC5 for the refinement of macromolecular crystal structures

21 April 2017

1 reference

Features and development of Coot

21 April 2017

1 reference

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

1 reference

MolProbity: all-atom structure validation for macromolecular crystallography

21 April 2017

1 reference

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13396

The structure and function of G-protein-coupled receptors

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13396

Crystallizing membrane proteins using lipidic mesophases

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13396

Serine and threonine residues bend alpha-helices in the chi(1) = g(-) conformation.

21 April 2017

1 reference

12 December 2020

Common structural requirements for heptahelical domain function in class A and class C G protein-coupled receptors

1 reference

12 December 2020

A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.

1 reference

12 December 2020

Mutational Analysis and Molecular Modeling of the Binding Pocket of the Metabotropic Glutamate 5 Receptor Negative Modulator 2-Methyl-6-(phenylethynyl)-pyridine

1 reference

12 December 2020

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

1 reference

12 December 2020

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

1 reference

12 December 2020

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

1 reference

12 December 2020

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

1 reference

12 December 2020

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

1 reference

12 December 2020

Molecular signatures of G-protein-coupled receptors

1 reference

12 December 2020

Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

1 reference

12 December 2020

Molecular mechanism of 7TM receptor activation--a global toggle switch model

1 reference

12 December 2020

Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).

1 reference

12 December 2020

Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

1 reference

12 December 2020

Amino acids in the second and third intracellular loops of the parathyroid Ca2+-sensing receptor mediate efficient coupling to phospholipase C.

1 reference

12 December 2020

Metabotropic glutamate receptor 5-negative allosteric modulators for the treatment of psychiatric and neurological disorders (2009-July 2013).

1 reference

12 December 2020

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.

1 reference

12 December 2020

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

1 reference

12 December 2020

Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators

1 reference

12 December 2020

Thermostabilization of the neurotensin receptor NTS1.

1 reference

12 December 2020

A G protein-coupled receptor at work: the rhodopsin model.

1 reference

12 December 2020

Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacology

1 reference

12 December 2020

[(3)H]-M-MPEP, a potent, subtype-selective radioligand for the metabotropic glutamate receptor subtype 5.

1 reference

12 December 2020

AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome

1 reference

12 December 2020

Altered G-protein coupling in an mGluR6 point mutant associated with congenital stationary night blindness

1 reference

12 December 2020

Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP.

1 reference

12 December 2020

Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13396

2 references

Consolidated OpenCitations Corpus – April 2017

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Dimensions Publication ID

10 March 2020

1029395386

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Fatcat ID

release_x5ixeryiknaljelmgfq3dpkaue

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Fatcat

https://api.fatcat.wiki/v0/release/x5ixeryiknaljelmgfq3dpkaue

24 November 2022

mapped directly with Wikidata item

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Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25042998%20AND%20SRC:MED&resulttype=core&format=json