Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration (Q27727708)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Dawang Zhou

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

23

Nathanael S Gray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Fuqin Fan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Zhixiang He

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lu-Lu Kong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Qinghua Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Quan Yuan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Shihao Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jinjin Ye

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Hao Liu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xiufeng Sun

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jing Geng

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lunzhi Yuan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lixin Hong

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Chen Xiao

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Weiji Zhang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xihuan Sun

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Yunzhan Li

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Ping Wang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lihong Huang

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xinrui Wu

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Zhiliang Ji

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Qiao Wu

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Lanfen Chen

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Cai-Hong Yun

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xianming Deng

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

12 June 2020

language of work or name

English

0 references

publication date

17 August 2016

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

352ra108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

The Hippo Signaling Pathway in Development and Cancer

12 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.AAF2304

A quantitative analysis of kinase inhibitor selectivity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.AAF2304

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.AAF2304

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.AAF2304

Wound repair and regeneration

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Wound repair and regeneration: mechanisms, signaling, and translation

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Stem Cell Therapies in Clinical Trials: Progress and Challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Drug-induced regeneration in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Lin28 enhances tissue repair by reprogramming cellular metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Regulation of mammalian Ste20 (Mst) kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Protein kinases of the Hippo pathway: regulation and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The Hippo pathway and human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The biology of YAP/TAZ: hippo signaling and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

YAP/TAZ at the Roots of Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Yes-associated protein is involved in proliferation and differentiation during postnatal liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

A review of acetaminophen poisoning

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Safety and efficacy of intravenous N-acetylcysteine for acetaminophen overdose: analysis of the Hunter Area Toxicology Service (HATS) database.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF2304

10.1126/SCITRANSLMED.AAF2304

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27535619%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference