Activation mechanism of endothelin ETB receptor by endothelin-1 (Q27727996)

7

0 references

Naoshi Dohmae

5

0 references

author name string

Wataru Shihoya

1

0 references

Tomohiro Nishizawa

2

0 references

Akiko Okuta

3

0 references

Kazutoshi Tani

4

0 references

Yoshinori Fujiyoshi

6

0 references

Tomoko Doi

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

8

0 references

language of work or name

English

0 references

publication date

5 September 2016

0 references

published in

Nature

0 references

volume

537

0 references

issue

7620

0 references

page(s)

363-368

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Endothelin: 20 years from discovery to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Endothelin system: the double-edged sword in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Regulation of blood pressure and salt homeostasis by endothelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Interaction of endothelin-1 with cloned bovine ETA receptors: biochemical parameters and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Interactions of endothelin receptor subtypes A and B with Gi, Go, and Gq in reconstituted phospholipid vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Endothelin 1 in cancer: biological implications and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

New therapeutics that antagonize endothelin: promises and frustrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Macitentan: entry-into-humans study with a new endothelin receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Ambrisentan, a non-peptide endothelin receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Molecular signatures of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structure of the agonist-bound neurotensin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Protein-protein interactions: general trends in the relationship between binding affinity and interfacial buried surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

The crystal structure of human endothelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Distributed computing and NMR constraint-based high-resolution structure determination: applied for bioactive Peptide endothelin-1 to determine C-terminal folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Conformational isomerism of endothelin in acidic aqueous media: a quantitative NOESY analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structural determinants for selective recognition of peptide ligands for endothelin receptor subtypes ETA and ETB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Alanine scan of endothelin: Importance of aromatic residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Identification of Receptor Binding and Activation Sites in Endothelin-1 by Use of Site-Directed Mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Activation and allosteric modulation of a muscarinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structural prerequisites for G-protein activation by the neurotensin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structural insights into µ-opioid receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

The dynamic process of β(2)-adrenergic receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Propagation of conformational changes during μ-opioid receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Allosteric sodium in class A GPCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

The structural basis of agonist-induced activation in constitutively active rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structure of an agonist-bound human A2A adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Characterization of endothelin receptors ETA and ETB expressed in COS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Palmitoylation of human endothelinB. Its critical role in G protein coupling and a differential requirement for the cytoplasmic tail by G protein subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Crystallizing membrane proteins using lipidic mesophases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Features and development of Coot

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Characterization of human endothelin B receptor and mutant receptors expressed in insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

[Lys(-2)-Arg(-1)]endothelin-1 solution structure by two-dimensional 1H-NMR: possible involvement of electrostatic interactions in native disulfide bridge formation and in biological activity decrease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Deciphering key features in protein structures with the new ENDscript server

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature

21 January 2018

1 reference

12 December 2020

Molecular cloning and characterization of the major endothelin receptor subtype in porcine cerebellum

1 reference

12 December 2020

Purification of an endothelin receptor from human placenta

1 reference

12 December 2020

Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism

1 reference

12 December 2020

Human endothelin receptor ETB. Amino acid sequence requirements for super stable complex formation with its ligand

1 reference

12 December 2020

D-amino acid scan of endothelin: importance of amino acids adjacent to cysteinyl residues in isomeric selectivity

1 reference

12 December 2020

Thermostabilization of the Human Endothelin Type B Receptor

1 reference

12 December 2020

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1 reference

12 December 2020

The quasi-irreversible nature of endothelin binding and G protein-linked signaling in cardiac myocytes.

1 reference

12 December 2020

Endothelin-1 analogues substituted at both position 18 and 19: highly potent endothelin antagonists with no selectivity for either receptor subtype ETA or ETB

1 reference

12 December 2020

Regulation and intracellular trafficking pathways of the endothelin receptors

1 reference

12 December 2020

Structure-activity relationship of endothelin: importance of charged groups

1 reference

12 December 2020

Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites

1 reference

12 December 2020