Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism. (Q27932046)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

DNA helicase SRS2 YJL092W

1 February 2020

main subject

1 reference

GOA release 2020-03-11

Nej1p YLR265C

1 reference

GOA release 2020-03-11

Lif1p YGL090W

1 reference

GOA release 2020-03-11

author

Stefan Åström

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Dana Vigasová

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Jiang Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Sidney D Carter

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Miroslav Chovanec

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

1 July 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 February 2020

published in

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

106

1 reference

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1 February 2020

issue

29

1 reference

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1 February 2020

page(s)

12037-12042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

1 February 2020

cites work

1 reference

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The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

20 March 2017

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A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio.

20 March 2017

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

20 March 2017

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20 March 2017

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NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae

20 March 2017

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20 March 2017

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Requirement for the SRS2 DNA helicase gene in non-homologous end joining in yeast

20 March 2017

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20 March 2017

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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

20 March 2017

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Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae

20 March 2017

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Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

20 March 2017

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

20 March 2017

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Characterization of postreplication repair in Saccharomyces cerevisiae and effects of rad6, rad18, rev3 and rad52 mutations

20 March 2017

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Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

20 March 2017

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One-step gene disruption in yeast

20 March 2017

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Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast

20 March 2017

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Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

20 March 2017

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SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

20 March 2017

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Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

20 March 2017

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Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

7 April 2017

1 reference

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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

22 April 2017

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Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

7 April 2017

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Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

7 April 2017

1 reference

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DNA helicase Srs2 disrupts the Rad51 presynaptic filament

7 April 2017

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Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

7 April 2017

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The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast

7 April 2017

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[12] One-step gene disruption in yeast

7 April 2017

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The Srs2 helicase activity is stimulated by Rad51 filaments on dsDNA: implications for crossover incidence during mitotic recombination

22 April 2017

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Nonhomologous end joining in yeast

29 September 2017

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Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation

29 September 2017

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Rejoining of DNA double-strand breaks as a function of overhang length

29 September 2017

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Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication

29 September 2017

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Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes

29 September 2017

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NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway

29 September 2017

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A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae

29 September 2017

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Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity

29 September 2017

1 reference

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DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair

29 September 2017

1 reference

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Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715516

The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715516

Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutants

29 September 2017

1 reference

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The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715516

Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover

2 June 2018

1 reference

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DUN1 encodes a protein kinase that controls the DNA damage response in yeast.

2 June 2018

1 reference

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Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0903869106

Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0903869106

Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0903869106

The DNA binding properties of Saccharomyces cerevisiae Rad51 protein

21 January 2018

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Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo

21 January 2018

1 reference

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Expression and purification of maltose-binding protein fusions.

27 November 2018

1 reference

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Requirement of yeast SGS1 and SRS2 genes for replication and transcription

27 November 2018

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12 December 2020

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

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12 December 2020

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

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[55] Genetic screens and selections for cell and nuclear fusion mutants

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0903869106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

release_4m2cyreycre73gip7nn7jne5we

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4m2cyreycre73gip7nn7jne5we

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19571008%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

2 references

1 December 2016