Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation (Q27939444)

PubMed

1 December 2016

title

Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation (English)

1 reference

PubMed

Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2 YHR164C

1 December 2016

main subject

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Hui-I Kao

series ordinal

1

0 references

Judith L Campbell

series ordinal

2

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Robert A Bambara

series ordinal

3

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language of work or name

English

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publication date

3 December 2004

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published in

1 reference

PubMed

1 December 2016

volume

279

0 references

issue

49

0 references

page(s)

50840-9

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cites work

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Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

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Tripartite structure of Saccharomyces cerevisiae Dna2 helicase/endonuclease

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A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

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On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing

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DNA structural elements required for FEN-1 binding

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Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

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A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

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Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

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Effect of flap modifications on human FEN1 cleavage.

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RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

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The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

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Dna2 of Saccharomyces cerevisiae possesses a single-stranded DNA-specific endonuclease activity that is able to act on double-stranded DNA in the presence of ATP.

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Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage

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A yeast gene required for DNA replication encodes a protein with homology to DNA helicases

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Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro

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Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1

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Benzo[a]pyrene-DNA adducts inhibit the DNA helicase activity of the bacteriophage T7 gene 4 protein.

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Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent

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Enzymes and reactions at the eukaryotic DNA replication fork

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The protein components and mechanism of eukaryotic Okazaki fragment maturation

21 January 2018

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Mutator specificity and disease: looking over the FENce

21 January 2018

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The pattern of sensitivity of yeast dna2 mutants to DNA damaging agents suggests a role in DSB and postreplication repair pathways

21 January 2018

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Mutations in Yeast Replication Proteins That Increase CAG/CTG Expansions Also Increase Repeat Fragility

21 January 2018

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Evidence that yeast SGS1, DNA2, SRS2, and FOB1 interact to maintain rDNA stability

21 January 2018

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Dna2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of Saccharomyces cerevisiae

21 January 2018

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The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants

21 January 2018

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Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication

21 January 2018

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The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409231200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017