Role of lncRNAs in Cellular Aging (Q28078986)

Sun Lei

series ordinal

2

1 reference

language of work or name

1 reference

6 December 2016

1 reference

Frontiers in Endocrinology

published in

1 reference

volume

7

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page(s)

151

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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

cites work

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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene

20 March 2017

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The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

20 March 2017

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Long noncoding RNA as modular scaffold of histone modification complexes

20 March 2017

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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

20 March 2017

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Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

20 March 2017

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

20 March 2017

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

20 March 2017

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A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains

20 March 2017

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A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced

20 March 2017

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

20 March 2017

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

20 March 2017

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TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

20 March 2017

The hallmarks of aging

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The DNA damage response: putting checkpoints in perspective

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

20 March 2017

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

20 March 2017

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Identification of a mammalian mitochondrial porphyrin transporter

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Super-enhancers in the control of cell identity and disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Ink4a/Arf expression is a biomarker of aging

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Landscape of transcription in human cells

20 March 2017

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The serial cultivation of human diploid cell strains

7 April 2017

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Long noncoding RNAs: functional surprises from the RNA world

7 April 2017

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

7 April 2017

1 reference

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

7 April 2017

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A DNA damage checkpoint response in telomere-initiated senescence

7 April 2017

1 reference

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Epigenetic regulation by long noncoding RNAs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

7 April 2017

1 reference

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Non-coding RNAs: regulators of disease

7 April 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Oncogenic long noncoding RNA FAL1 in human cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Novel loci and pathways significantly associated with longevity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Super-enhancer lncs to cardiovascular development and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Senescence-associated Long Non-coding RNA (SALNR) Delays Oncogene-induced Senescence through NF90 Regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Urothelial cancer associated 1: a long noncoding RNA with a crucial role in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

RNA sequencing from human neutrophils reveals distinct transcriptional differences associated with chronic inflammatory states

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Integrator mediates the biogenesis of enhancer RNAs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

The lncRNA MIR31HG regulates p16(INK4A) expression to modulate senescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

What are super-enhancers?

29 September 2017

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Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

A novel role for lncRNAs in cell cycle control during stress adaptation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Regulation of transcription by long noncoding RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

7SL RNA represses p53 translation by competing with HuR

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Cellular senescence: from physiology to pathology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

The role of senescent cells in ageing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Long non-coding RNA Loc554202 regulates proliferation and migration in breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Long non-coding RNAs: modulators of nuclear structure and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Emerging evidence for functional peptides encoded by short open reading frames

29 September 2017

1 reference

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Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Long non-coding RNAs: new players in cell differentiation and development

29 September 2017

1 reference

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Computational prediction of associations between long non-coding RNAs and proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

29 September 2017

1 reference

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Long noncoding RNAs usher in a new era in the biology of enhancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

lincRNAs: genomics, evolution, and mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Senescence-associated lncRNAs: senescence-associated long noncoding RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Telomeres and age-related disease: how telomere biology informs clinical paradigms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

LincRNA-p21 suppresses target mRNA translation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

The essence of senescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Characterization of the RNA content of chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Differential p53-independent outcomes of p19(Arf) loss in oncogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells

29 September 2017

1 reference

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Antagonistic pleiotropy and p53.

29 September 2017

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Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

p16INK4a induces an age-dependent decline in islet regenerative potential

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5138193

Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes

29 September 2017

1 reference

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Molecular genetics of multiple endocrine neoplasia types 1 and 2.

29 September 2017

1 reference

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The signals and pathways activating cellular senescence

29 September 2017

1 reference

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Telomerase RNA: a flexible RNA scaffold for telomerase biosynthesis

29 September 2017

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Reversal of human cellular senescence: roles of the p53 and p16 pathways

29 September 2017

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Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

29 September 2017

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

29 September 2017

1 reference

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The mitochondrial lncRNA ASncmtRNA-2 is induced in aging and replicative senescence in Endothelial Cells

29 September 2017

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LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint

2 June 2018

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Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes

2 June 2018

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Expression of a novel non-coding mitochondrial RNA in human proliferating cells.

2 June 2018

1 reference

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Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons

2 June 2018

1 reference

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Cellular senescence, cancer, and organismal aging: a paradigm shift

21 January 2018

1 reference

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

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Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes

21 January 2018

1 reference

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21 January 2018

RNA switch at enhancers

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2016.00151

Going the distance: a current view of enhancer action

21 January 2018

1 reference

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ATM, MacroH2A.1, and SASP: The Checks and Balances of Cellular Senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2016.00151

21 January 2018

1 reference

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Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3

27 November 2018

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12 December 2020

Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

1 reference

12 December 2020

Failure of stress-induced downregulation of Bcl-2 contributes to apoptosis resistance in senescent human diploid fibroblasts

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12 December 2020

Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences

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12 December 2020

Identifiers

DOI

10.3389/FENDO.2016.00151

0 references

1 reference

PubMed publication ID

27999563

1 reference