Novel Allosteric Modulators of G Protein-coupled Receptors (Q28081112)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

review article

1 reference

title

Novel Allosteric Modulators of G Protein-coupled Receptors (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

17 February 2020

main subject

0 references

author

Patrick R Gentry

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Patrick M. Sexton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Arthur Christopoulos

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

3

Arthur Christopoulos

1 reference

Patrick R. Gentry

1

1 reference

Patrick M. Sexton

2

1 reference

language of work or name

1 reference

22 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 February 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

290

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

32

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

19478-19488

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

Endogenous allosteric modulators of G protein-coupled receptors

17 February 2020

cites work

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control

2 June 2018

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Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

2 June 2018

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Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes

2 June 2018

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Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo

2 June 2018

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Interactions of alcuronium, TMB-8, and other allosteric ligands with muscarinic acetylcholine receptors: studies with chimeric receptors.

2 June 2018

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Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.

2 June 2018

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Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity

2 June 2018

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Allosteric modulation of muscarinic acetylcholine receptors.

21 January 2018

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Inhibition of the actions of carbachol and DFP on guinea pig isolated atria by alkane-bis-ammonium compounds

21 January 2018

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A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor

21 January 2018

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Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors

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https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Interaction studies of multiple binding sites on m4 muscarinic acetylcholine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Amiloride derivatives and a nonpeptidic antagonist bind at two distinct allosteric sites in the human gonadotropin-releasing hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

XMetA, an allosteric monoclonal antibody to the insulin receptor, improves glycaemic control in mice with diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1β antibody with differential receptor-modulating properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Advancing the drug discovery and development process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

BRET analysis of GPCR oligomerization: newer does not mean better

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Synthesis and pharmacological evaluation of analogues of benzyl quinolone carboxylic acid (BQCA) designed to bind irreversibly to an allosteric site of the M ₁ muscarinic acetylcholine receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Differential activation and modulation of the glucagon-like peptide-1 receptor by small molecule ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R115.662759

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528113

Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528113

A critical pocket close to the glutamate binding site of mGlu receptors opens new possibilities for agonist design

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26100627

12 December 2020

inferred from PubMed ID database lookup

Reversing systemic inflammatory response syndrome with chemokine receptor pepducins

1 reference

https://pubmed.ncbi.nlm.nih.gov/26100627

12 December 2020

inferred from PubMed ID database lookup

Modification of the binding properties of muscarinic receptors by gallamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/26100627

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.R115.662759

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

release_ykjg66snyrhxvm3nclswgvfrzq

17 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ykjg66snyrhxvm3nclswgvfrzq

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100627%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26100627

2 references