Functions of the influenza A virus NS1 protein in antiviral defense (Q28083893)

Crossref

language of work or name

1 reference

June 2015

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Current opinion in virology

published in

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volume

12

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page(s)

1-6

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Suppression of the antiviral response by an influenza histone mimic

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Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

20 March 2017

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Structural Insights into RNA Recognition by RIG-I

20 March 2017

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A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain

20 March 2017

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

20 March 2017

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

20 March 2017

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Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

20 March 2017

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Structure of NS1A effector domain from the influenza A/Udorn/72 virus

20 March 2017

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Structural basis for dsRNA recognition by NS1 protein of influenza A virus

20 March 2017

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Structural basis for suppression of a host antiviral response by influenza A virus

20 March 2017

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Structure of an avian influenza A virus NS1 protein effector domain

20 March 2017

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Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response

20 March 2017

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The H5N1 influenza virus NS genes selected after 1998 enhance virus replication in mammalian cells

20 March 2017

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Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes

20 March 2017

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Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

20 March 2017

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

20 March 2017

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Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

20 March 2017

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A novel RNA-binding motif in influenza A virus non-structural protein 1

20 March 2017

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NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I

20 March 2017

1 reference

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The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

20 March 2017

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Dimer interface of the effector domain of non-structural protein 1 from influenza A virus: an interface with multiple functions

20 March 2017

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Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

20 March 2017

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Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

20 March 2017

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Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

20 March 2017

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LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3.

29 September 2017

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The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins

29 September 2017

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The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

29 September 2017

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Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription

29 September 2017

1 reference

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Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

29 September 2017

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Innate immunity to virus infection.

29 September 2017

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Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

29 September 2017

1 reference

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Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

29 September 2017

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Multiple anti-interferon actions of the influenza A virus NS1 protein

29 September 2017

1 reference

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A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

29 September 2017

1 reference

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The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism

29 September 2017

1 reference

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IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

29 September 2017

1 reference

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The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway

29 September 2017

1 reference

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The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is unique

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470714

Two nuclear location signals in the influenza virus NS1 nonstructural protein

29 September 2017

1 reference

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A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

29 September 2017

1 reference

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Protective role of LGP2 in influenza virus pathogenesis.

2 June 2018

1 reference

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Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode

2 June 2018

1 reference