A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay (Q28115899)

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31 May 2020

Melanie Ott

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Nevan J Krogan

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Erik Verschueren

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4 January 2017

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John Von Dollen

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4 January 2017

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Tasha Johnson

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Billy Newton

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4 January 2017

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Priya Shah

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4 January 2017

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Julie Horner

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4 January 2017

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G Renuka Kumar

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Jeffrey R Johnson

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22 January 2015

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4 January 2017

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57

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cites work

Hepatitis C virus core protein binds to a DEAD box RNA helicase

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Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

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Viral immune modulators perturb the human molecular network by common and unique strategies

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PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs

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Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs

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The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates

20 March 2017

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Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay

20 March 2017

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Defining the human deubiquitinating enzyme interaction landscape

20 March 2017

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Disassembly of exon junction complexes by PYM

20 March 2017

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An efficient protein complex purification method for functional proteomics in higher eukaryotes

20 March 2017

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Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

20 March 2017

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Identification and comparative analysis of hepatitis C virus-host cell protein interactions

20 March 2017

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Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein

20 March 2017

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Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets

20 March 2017

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Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

20 March 2017

1 reference

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Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication

20 March 2017

1 reference

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One step at a time: endoplasmic reticulum-associated degradation

20 March 2017

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Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation

20 March 2017

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Subcellular Localization and Topology of the p7 Polypeptide of Hepatitis C Virus

20 March 2017

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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

20 March 2017

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Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation

20 March 2017

1 reference

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Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

20 March 2017

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Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro

20 March 2017

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Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

20 March 2017

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Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

20 March 2017

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Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain

20 March 2017

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Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

20 March 2017

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A genome-wide genetic screen for host factors required for hepatitis C virus propagation

20 March 2017

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A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

20 March 2017

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Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex

20 March 2017

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Unusual architecture of the p7 channel from hepatitis C virus

20 March 2017

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

20 March 2017

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20 March 2017

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Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches

20 March 2017

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Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

20 March 2017

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ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

7 April 2017

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Activation and evasion of antiviral innate immunity by hepatitis C virus.

29 September 2017

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Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.

29 September 2017

1 reference

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The Golgi puppet master: COG complex at center stage of membrane trafficking interactions.

29 September 2017

1 reference

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Cell-cell contact-mediated hepatitis C virus (HCV) transfer, productive infection, and replication and their requirement for HCV receptors

29 September 2017

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Hepatitis C virus: virology and life cycle

29 September 2017

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Viroporins: structure and biological functions.

29 September 2017

1 reference

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RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infection

29 September 2017

1 reference

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Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy

29 September 2017

1 reference

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Turning hepatitis C into a real virus

29 September 2017

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Modulation of programmed cell death pathways by the hepatitis C virus

29 September 2017

1 reference

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Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

29 September 2017

1 reference

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Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images

29 September 2017

1 reference

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CORUM: the comprehensive resource of mammalian protein complexes--2009

29 September 2017

1 reference

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Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

29 September 2017

1 reference

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Molecular determinants for subcellular localization of hepatitis C virus core protein

29 September 2017

1 reference

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

29 September 2017

1 reference

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Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif

29 September 2017

1 reference

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The ever-increasing complexities of the exon junction complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Interaction of hepatitis C virus proteins with host cell membranes and lipids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

The host nonsense-mediated mRNA decay pathway restricts Mammalian RNA virus replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Nonsense-mediated mRNA decay modulates immune receptor levels to regulate plant antibacterial defense

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Nonsense-mediated decay serves as a general viral restriction mechanism in plants

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

TIP47 plays a crucial role in the life cycle of hepatitis C virus

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Sofosbuvir for previously untreated chronic hepatitis C infection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4305532

HCV core protein localizes in the nuclei of nonparenchymal liver cells from chronically HCV-infected patients

27 November 2018

1 reference

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10.1016/J.MOLCEL.2014.12.028

27 November 2018

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31 May 2020

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31 May 2020

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