Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro (Q28118564)

4 January 2017

title

Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro (English)

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Telomerase associated protein 1

4 January 2017

main subject

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GOA release 2020-03-11

tumor protein p53

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GOA release 2020-03-11

p53 binding

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GOA release 2020-03-11

molecular interaction

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H. Li

1

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4 January 2017

Y. Cao

2

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4 January 2017

M. C. Berndt

3

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4 January 2017

J. W. Funder

4

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4 January 2017

J. P. Liu

5

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4 January 2017

language of work or name

English

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publication date

18 November 1999

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4 January 2017

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4 January 2017

volume

18

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4 January 2017

issue

48

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4 January 2017

page(s)

6785–6794

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Increased activity of p53 in senescing fibroblasts

4 January 2017

cites work

1 reference

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Extension of life-span by introduction of telomerase into normal human cells

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Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation

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Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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The catalytic subunit of yeast telomerase

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Activation of telomerase in a human tumor

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The RNA component of human telomerase

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Telomerase activity in human leukemic cell lines is inhibited by antisense pentadecadeoxynucleotides targeted against c-myc mRNA.

21 January 2018

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Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts

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Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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Telomere length regulation

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Telomeres and senescence: the history, the experiment, the future

21 January 2018

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A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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Telomerase, Cell Immortality, and Cancer

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A mammalian telomerase-associated protein

21 January 2018

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Human telomerase contains evolutionarily conserved catalytic and structural subunits

21 January 2018

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Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

21 January 2018

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21 January 2018

p53: puzzle and paradigm

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Essential role of mouse telomerase in highly proliferative organs

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p53, the cellular gatekeeper for growth and division

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Telomerase is controlled by protein kinase Calpha in human breast cancer cells

21 January 2018

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Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang

21 January 2018

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Reverse transcriptase motifs in the catalytic subunit of telomerase

21 January 2018

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

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Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

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TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

21 January 2018

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Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

21 January 2018

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Severe growth defect in mouse cells lacking the telomerase RNA component

21 January 2018

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Tumor suppressors. Teaming up to restrain cancer.

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Telomerase activity does not always imply telomere maintenance

21 January 2018

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Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

21 January 2018

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Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer

21 January 2018

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Analysis of a protein-binding domain of p53

21 January 2018

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Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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A survey of telomerase activity in human cancer

21 January 2018

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Functional Evidence for an RNA Template in Telomerase

21 January 2018

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Molecular cloning of bovine telomerase RNA.

21 January 2018

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21 January 2018

Myc activates telomerase

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Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

21 January 2018

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Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells

21 January 2018

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Direct activation of TERT transcription by c-MYC.

21 January 2018

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p53: guardian of cellular senescence

21 January 2018

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Telomeres: beginning to understand the end.

21 January 2018

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Ending up with the right partner

21 January 2018

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21 January 2018

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7 January 2021

Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation

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7 January 2021

Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Dimensions Publication ID

Identifiers

DOI

10.1038/SJ.ONC.1203061

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1021588050

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