CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism (Q28181429)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14594818%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism (English)

1 reference

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CAMP responsive element binding protein 1

20 December 2019

main subject

1 reference

Early B cell factor 1

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Apurinic/apyrimidinic endonuclease 1

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Paired box 5

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CD40 antigen

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author

Mikael Sigvardsson

5

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20 December 2019

Carlo Pucillo

7

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20 December 2019

author name string

Sonia Merluzzi

1

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20 December 2019

Massimo Moretti

2

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20 December 2019

Sandro Altamura

3

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20 December 2019

Patty Zwollo

4

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20 December 2019

Gaetano Vitale

6

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20 December 2019

language of work or name

English

0 references

publication date

31 October 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14594818%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 December 2019

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14594818%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

279

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20 December 2019

issue

3

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20 December 2019

page(s)

1777-1786

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The role of CD40 and its ligand (gp39) in peripheral and central tolerance and its contribution to autoimmune disease

20 December 2019

cites work

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The TNF and TNF receptor superfamilies: integrating mammalian biology

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Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2

21 January 2018

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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The Pax-5 gene is alternatively spliced during B-cell development

21 January 2018

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Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

21 January 2018

1 reference

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Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

21 January 2018

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The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

21 January 2018

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A developmentally modulated chromatin structure at the mouse immunoglobulin kappa 3' enhancer

21 January 2018

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In vivo occupancy of the kappa light chain enhancers in primary pro- and pre-B cells: a model for kappa locus activation

21 January 2018

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An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene

21 January 2018

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Transcription of the blk gene in human B lymphocytes is controlled by two promoters

21 January 2018

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Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1

21 January 2018

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A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation

21 January 2018

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Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts

21 January 2018

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NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation

21 January 2018

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An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

21 January 2018

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21 January 2018

An APE that proofreads

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Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

21 January 2018

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The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

21 January 2018

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Expression and subcellular localization of human AP endonuclease 1 (HAP1/Ref-1) protein: a basis for its role in human disease

21 January 2018

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Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression

21 January 2018

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Olf-1-binding site: characterization of an olfactory neuron-specific promoter motif

21 January 2018

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Purification of early-B-cell factor and characterization of its DNA-binding specificity

21 January 2018

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EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

21 January 2018

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Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

21 January 2018

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The B29 (immunoglobulin beta-chain) gene is a genetic target for early B-cell factor

21 January 2018

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Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by activating NF-kappa B via Ref-1.

21 January 2018

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Co-regulation of two gene activities by tetracycline via a bidirectional promoter.

21 January 2018

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Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

21 January 2018

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Transformation of rat cells by DNA of human adenovirus 5

21 January 2018

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Redox potential controls the structure and DNA binding activity of the paired domain

21 January 2018

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Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter

21 January 2018

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Redox regulation of fos and jun DNA-binding activity in vitro

21 January 2018

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Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305418200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14594818%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference