Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding (Q28214375)

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R Yuan

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Y X Ma

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J Xiong

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Q Meng

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M Erdos

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J N Zhao

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I D Goldberg

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R G Pestell

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E M Rosen

BRCA1-associated growth arrest is RB-dependent

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language of work or name

English

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publication date

9 August 2001

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published in

Oncogene

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volume

20

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issue

35

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page(s)

4827-41

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cites work

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The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

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7 January 2021

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7 January 2021

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

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7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

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7 January 2021