Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines (Q28214508)

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Silke Fähnrich

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Yvonne Lis

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Elisabeth Becker

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Roderick A F MacLeod

International Journal of Cancer

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language of work or name

English

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publication date

1 July 2002

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published in

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volume

100

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issue

1

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page(s)

49-56

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cites work

Oncogenic transcription factors in the human acute leukemias

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CD30-positive large cell lymphomas ('Ki-1 lymphoma') are associated with a chromosomal translocation involving 5q35.

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Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

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ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35).

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Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

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Biochemical detection of novel anaplastic lymphoma kinase proteins in tissue sections of anaplastic large cell lymphoma.

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Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity

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TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors

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Translocations involving anaplastic lymphoma kinase (ALK).

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

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Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor

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Dicistronic transcription units for gene expression in mammalian cells

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Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

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Expression of the ALK tyrosine kinase gene in neuroblastoma

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Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways

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The trk family of receptors mediates nerve growth factor and neurotrophin-3 effects in melanocytes.

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Neurotrophin receptors, tumor progression and tumor maturation

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Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin

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Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway

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Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo

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Expression of the oncogenic NPM-ALK chimeric protein in human lymphoid T-cells inhibits drug-induced, but not Fas-induced apoptosis.

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Expression of TrkA, TrkB and TrkC in human neuroblastomas

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