An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells (Q28217100)

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Annet Hammacher

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Andrea M Douglas

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Geraldine A Goss

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Rachel K Mansfield

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John K Heath

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C Glenn Begley

Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade.

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language of work or name

English

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publication date

17 January 2002

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published in

Oncogene

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volume

21

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issue

3

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page(s)

460-74

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cites work

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Signaling of type II oncostatin M receptor

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Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

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STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

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The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

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The oncostatin M signalling pathway: reversing the neoplastic phenotype?

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

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Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers

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Activation of Jak-Stat and MAPK2 pathways by oncostatin M leads to growth inhibition of human glioma cells.

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The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor

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IL-6 cytokine family and signal transduction: a model of the cytokine system

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Activation of EGF receptor family members suppresses the cytotoxic effects of tumor necrosis factor-alpha.

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Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth

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Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

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ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

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Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

21 January 2018

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Oncostatin M (OSM) inhibits the differentiation of pluripotent embryonic stem cells in vitro

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Positive immunostaining for platelet derived growth factor (PDGF) is an adverse prognostic factor in patients with advanced breast cancer

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines

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Kit signal transduction

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IGF-I receptor signalling in transformation and differentiation

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Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Epidermal growth factor receptors in breast cancer: Association with early relapse and death, poor response to hormones and interactions with neu

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Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines

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Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells

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Control of human breast cancer by estrogen, growth factors, and oncogenes

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Expression and function of members of the cytokine receptor superfamily on breast cancer cells

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Oncostatin M induces the differentiation of breast cancer cells

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A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

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Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

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p38MAP kinase is a negative regulator for ERK1/2-mediated growth of AIDS-associated Kaposi's sarcoma cells

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A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

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The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands

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Modulation of hepatic acute phase gene expression by epidermal growth factor and Src protein tyrosine kinases in murine and human hepatic cells

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