Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma (Q28236409)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17628016%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma (English)

1 reference

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2 January 2020

0 references

1 reference

5

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2 January 2020

William Matsui

6

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Sara Grazia Maria Piccirillo

2 January 2020

7

1 reference

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2 January 2020

Francesco DiMeco

9

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2 January 2020

Alessandro Olivi

10

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2 January 2020

11

Charles G Eberhart

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2 January 2020

author name string

Eli E Bar

1

1 reference

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2 January 2020

Aneeka Chaudhry

2

1 reference

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2 January 2020

Alex Lin

3

1 reference

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2 January 2020

Xing Fan

4

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2 January 2020

Angelo L Vescovi

8

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2 January 2020

language of work or name

English

0 references

publication date

12 July 2007

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2 January 2020

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2 January 2020

volume

25

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2 January 2020

issue

10

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2 January 2020

page(s)

2524-2533

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

2 January 2020

cites work

1 reference

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In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

20 March 2017

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20 March 2017

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

20 March 2017

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The Hedgehog response network: sensors, switches, and routers

20 March 2017

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Cancerous stem cells can arise from pediatric brain tumors

20 March 2017

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

20 March 2017

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Characterization of the physical interaction of Gli proteins with SUFU proteins

20 March 2017

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Small molecule modulation of Smoothened activity

20 March 2017

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Patched and smoothened mRNA expression in human astrocytic tumors inversely correlates with histological malignancy

20 March 2017

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Hedgehog signaling in animal development: paradigms and principles

20 March 2017

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Stem cells, cancer, and cancer stem cells

20 March 2017

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

20 March 2017

1 reference

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Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

20 March 2017

1 reference

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

20 March 2017

1 reference

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Identification of an amplified, highly expressed gene in a human glioma

20 March 2017

1 reference

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Sonic hedgehog regulates the growth and patterning of the cerebellum

20 March 2017

1 reference

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The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis

20 March 2017

1 reference

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Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

20 March 2017

1 reference

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

20 March 2017

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

7 April 2017

1 reference

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Tumour stem cells and drug resistance

7 April 2017

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Notch signaling enhances nestin expression in gliomas

7 April 2017

1 reference

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Hedgehog signaling promotes medulloblastoma survival via Bc/II

29 September 2017

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HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

29 September 2017

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Neoplastic stem cells: a novel therapeutic target in clinical oncology

29 September 2017

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Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

29 September 2017

1 reference

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Killing time for cancer stem cells (CSC): discovery and development of selective CSC inhibitors.

29 September 2017

1 reference

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29 September 2017

Brain tumour stem cells

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Stem cells in prostate and prostate cancer development

29 September 2017

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c-myc overexpression causes anaplasia in medulloblastoma

29 September 2017

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29 September 2017

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Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

29 September 2017

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Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic

29 September 2017

1 reference

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Communicating with Hedgehogs

29 September 2017

1 reference

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Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

29 September 2017

1 reference

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

29 September 2017

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CD133, a novel marker for human prostatic epithelial stem cells.

29 September 2017

1 reference

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Therapeutic implications of cancer stem cells.

29 September 2017

1 reference

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Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

29 September 2017

1 reference

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Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

29 September 2017

1 reference

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Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

29 September 2017

1 reference

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Pathways and consequences: Hedgehog signaling in human disease.

29 September 2017

1 reference

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Malignant glioma: genetics and biology of a grave matter.

29 September 2017

1 reference

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Gliomagenesis: genetic alterations and mouse models

29 September 2017

1 reference

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Gli proteins and Hedgehog signaling: development and cancer

29 September 2017

1 reference

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Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation

29 September 2017

1 reference

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Isolation of primitive human bone marrow hematopoietic progenitor cells using Hoechst 33342 and Rhodamine 123.

29 September 2017

1 reference

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In vivo and in vitro characterization of long-term repopulating primitive hematopoietic cells isolated by sequential Hoechst 33342-rhodamine 123 FACS selection

29 September 2017

1 reference

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Transplantation of hematopoietic stem cells obtained by a combined dye method fractionation of murine bone marrow

29 September 2017

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

29 September 2017

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Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells.

2 June 2018

1 reference

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Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity.

27 November 2018

1 reference

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Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.

27 November 2018

1 reference

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Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610257

Medulloblastoma growth inhibition by hedgehog pathway blockade

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610257

Paucity of retinoic acid receptor alpha (RAR alpha) nuclear immunostaining in gliomas and inability of retinoic acid to influence neural cell adhesion molecule (NCAM) expression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610257

CD133+ cell selection is an alternative to CD34+ cell selection for ex vivo expansion of hematopoietic stem cells

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17628016

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1634/STEMCELLS.2007-0166

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17628016%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17628016%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

2 references