Neoplastic stem cells: a novel therapeutic target in clinical oncology (Q36622723)

15 August 2017

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title

Neoplastic stem cells: a novel therapeutic target in clinical oncology (English)

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15 August 2017

neoplastic stem cells

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Axel Schulenburg

1

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15 August 2017

Herbert Ulrich-Pur

2

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15 August 2017

Dietmar Thurnher

3

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15 August 2017

Boban Erovic

4

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15 August 2017

Stefan Florian

5

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15 August 2017

Wolfgang R Sperr

6

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15 August 2017

Peter Kalhs

7

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15 August 2017

Brigitte Marian

8

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15 August 2017

Friedrich Wrba

9

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15 August 2017

Christoph C Zielinski

10

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15 August 2017

Peter Valent

11

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15 August 2017

language of work or name

English

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publication date

1 November 2006

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15 August 2017

9

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inferred from page(s)

published in

Cancer

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15 August 2017

107

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15 August 2017

10

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15 August 2017

2512-2520

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Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny. The 10th Walter Hubert Lecture

15 August 2017

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https://api.crossref.org/works/10.1002%2FCNCR.22277

The role of stem cells and gap junctional intercellular communication in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Deciphering the mammary epithelial cell hierarchy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Increased immature hematopoietic progenitor cells CD34+/CD38dim in myelodysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Molecular monitoring of chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

Stem cells in differentiation and neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cellular origin of cancer: dedifferentiation or stem cell maturation arrest?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Multipotent, dedifferentiated cancer stem-like cells from brain gliomas.

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Redefining cellular phenotypy based on embryonic, adult, and cancer stem cell biology

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Stem Cells and Cancer: Two Faces of Eve

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Applying the principles of stem-cell biology to cancer

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancer stem cells in human gastrointestinal cancers

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancer stem cells: an old idea--a paradigm shift

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancer stem cells: lessons from leukemia.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Tumour stem cells and drug resistance

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Repopulation of cancer cells during therapy: an important cause of treatment failure

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancer stem cells: are we missing the target?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Therapeutic implications of cancer stem cells.

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Breast cancer, stem cells and prospects for therapy.

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Brain tumor stem cells: new targets for clinical treatments?

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Delivering cancer stem cell therapies - a role for nanomedicines?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Profiling cancer stem cells using protein array technology

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Strategies to eliminate cancer stem cells: clinical implications

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancer stem cells and therapeutic perspectives.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Prospective identification of tumorigenic breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

CD133, a novel marker for human prostatic epithelial stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Prospective identification of tumorigenic prostate cancer stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cancerous stem cells can arise from pediatric brain tumors

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Identification of human brain tumour initiating cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

https://api.crossref.org/works/10.1002%2FCNCR.22277

1 reference

7 January 2021

Osteoblastic cells regulate the haematopoietic stem cell niche

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Identification of the haematopoietic stem cell niche and control of the niche size

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Isolation of a candidate human hematopoietic stem-cell population

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A severe combined immunodeficiency mutation in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Transfer of a functional human immune system to mice with severe combined immunodeficiency

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Infection of the SCID-hu mouse by HIV-1

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Human immunodeficiency virus infection of human-PBL-SCID mice

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https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

SCID (severe combined immunodeficiency) mice as a new system to investigate metastasis of human tumors

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Engraftment of severe combined immune deficient/beige mice with bovine foetal lymphoid tissues

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

AC133-2, a novel isoform of human AC133 stem cell antigen

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Identification of a putative intestinal stem cell and early lineage marker; musashi-1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A putative human breast stem cell population is enriched for steroid receptor-positive cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Expression of neural RNA-binding proteins in the postnatal CNS: implications of their roles in neuronal and glial cell development.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Gap junctions and the regulation of cellular functions of stem cells during development and differentiation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Isolation and characterization of normal adult human epithelial pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Mammary stem cells come of age, prospectively

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Purification and unique properties of mammary epithelial stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Epithelial progenitors in the normal human mammary gland

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Skeletal myoblast transplantation for repair of myocardial necrosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Isolation of multipotent adult stem cells from the dermis of mammalian skin

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Purification and characterization of mouse hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Detection of molecular targets on the surface of CD34+/CD38-- stem cells in various myeloid malignancies.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Calicheamicin gamma 1I: an antitumor antibiotic that cleaves double-stranded DNA site specifically

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

CD44: a new means to inhibit acute myeloid leukemia cell proliferation via p27Kip1

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Identifying cancer stem cells in solid tumors: case not proven

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Recent translational research: stem cells as the roots of breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

CD44 promotes resistance to apoptosis in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Stem cell in gastrointestinal structure and neoplastic development

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Integrin beta1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Malignant progenitors from patients with CD87+ acute myelogenous leukemia are sensitive to a diphtheria toxin-urokinase fusion protein

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Chronic myelogenous leukaemia--new therapeutic principles.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Emergence of Ph negative clones in chronic myeloid leukemia (CML) patients in complete cytogenetic remission after therapy with imatinib mesylate (STI).

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Structural basis of the Axin-adenomatous polyposis coli interaction

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

The Hedgehog and Wnt signalling pathways in cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

A role for Wnt signalling in self-renewal of haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Multiple niches for Notch in cancer: context is everything

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

An overview of the Notch signalling pathway

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Survival of acute myeloid leukemia cells requires PI3 kinase activation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Antileukemic activity of rapamycin in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22277

7 January 2021

Identifiers

DOI

10.1002/CNCR.22277

1 reference

release_ghhpsdmzkjhrxpktvhg7ruecpm

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ghhpsdmzkjhrxpktvhg7ruecpm

24 November 2022

mapped directly with Wikidata item

1 reference